1,351
edits
Changes
Jump to navigation
Jump to search
no edit summary
*Large, enveloped, negative-sense RNA virus
*Large, enveloped, negative-sense RNA virus
*'''Bullet-shaped''' with short glycoprotein spikes
*'''Bullet-shaped''' with short glycoprotein spikes
=Types and Subtypes=
Two Genera:
#Lyssaviruses: 7 genotypes
##'''Genotype 1''' is '''classical rabies'''
##Genotypes 2-7 more limited in distribution
##Genotype 4 infects '''insectivorous bats'''
#Vesiculoviruses are all '''exotic''' to the UK:
##Vesicular Stomatitis Virus
##Ephemeral Fever
##Fish Rhabdoviruses, such as viral hemorrhagic syndrome and infectious haematopoetic necrosis virus
=Virulence and Pathogenesis=
=Virulence and Pathogenesis=
*Rabies is a '''NOTIFIABLE''' zoonosis
*Rabies is a '''NOTIFIABLE''' zoonosis
*Rabies is found worldwide, though currently considered exotic to the UK and Australia
*Rabies is found worldwide, though currently considered exotic to the UK and Australia
Host Range:
*All mammals are susceptible
**Very susceptible: foxes, jackals, wolves
**Susceptible (10,000x virus necessary to infect): cats, rodents, bats, skunks, cattle, mongooses
**Moderately susceptible (100,000x virus necessary to infect): dogs, sheep, goats, horses, primates
*Isolates can show to some species specificity in their reservoir host
*Reservoir species by region:
*Reservoir species by region:
{| style="width:60%; height:200px" border="1" align=center
{| style="width:60%; height:200px" border="1" align=center
*Immune recovered animals are rare, but are not shown to be infections
*Immune recovered animals are rare, but are not shown to be infections
=Types and Subtypes=
=Diagnosis=
=Rabies Control=
=Rabies Control=
*Antigenicity allows a single antigenic type to vaccinate
*Antigenicity allows a single antigenic type to vaccinate