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Feline Infectious Peritonitis (view source)
Revision as of 21:54, 16 October 2008
, 21:54, 16 October 2008New page: {{unfinished}} {{toplink |linkpage =Viruses |linktext =VIRUSES |sublink1=Coronaviridae |subtext1=CORONAVIRUSES |pagetype =Bugs }} <br> ====Antigenicity==== *FIP occurs in 5-10% of cats i...
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{{toplink
|linkpage =Viruses
|linktext =VIRUSES
|sublink1=Coronaviridae
|subtext1=CORONAVIRUSES
|pagetype =Bugs
}}
<br>
====Antigenicity====
*FIP occurs in 5-10% of cats infected with Feline Enteric Coronavirus (FECoV), which is quite common
*It is therefore antigenically indistinguishable from FECoV
====Hosts====
*Domestic and wild cats
====Pathogenesis====
*FECoV may cause mild respiratory symptoms and diarrhoea but is often asymptomatic
*Weeks, months or years may intervene between localized primary FECoV infection and FIP development
*FIP gains ability to replicate in monocytes and macrophages
*FECoV replicates in the gut, but FIP spreads systemically in the circulation
*Almost invariably '''fatal'''
*Failure of the immune system to clear antibody-antigen complexes leads to '''immune-mediated disease'''
**Deposited complexes cause '''inflammation''' and '''exudation'''
**This leads to characteristic '''oedema''' as fibrin-rich serum escapes to intercellular spaces
*For more, see [[Intestines Granulomatous Enteritis - Pathology#Feline Infectious Peritonitis|here]]
====Epidemiology====
====Diagnosis====
*Serology is impossible as most cats will have antibody to FECoV
====Control====
{{toplink
|linkpage =Viruses
|linktext =VIRUSES
|sublink1=Coronaviridae
|subtext1=CORONAVIRUSES
|pagetype =Bugs
}}
<br>
====Antigenicity====
*FIP occurs in 5-10% of cats infected with Feline Enteric Coronavirus (FECoV), which is quite common
*It is therefore antigenically indistinguishable from FECoV
====Hosts====
*Domestic and wild cats
====Pathogenesis====
*FECoV may cause mild respiratory symptoms and diarrhoea but is often asymptomatic
*Weeks, months or years may intervene between localized primary FECoV infection and FIP development
*FIP gains ability to replicate in monocytes and macrophages
*FECoV replicates in the gut, but FIP spreads systemically in the circulation
*Almost invariably '''fatal'''
*Failure of the immune system to clear antibody-antigen complexes leads to '''immune-mediated disease'''
**Deposited complexes cause '''inflammation''' and '''exudation'''
**This leads to characteristic '''oedema''' as fibrin-rich serum escapes to intercellular spaces
*For more, see [[Intestines Granulomatous Enteritis - Pathology#Feline Infectious Peritonitis|here]]
====Epidemiology====
====Diagnosis====
*Serology is impossible as most cats will have antibody to FECoV
====Control====