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New page: {{unfinished}} {{toplink |linkpage =Viruses |linktext =VIRUSES |sublink1=Flaviviridae |subtext1=FLAVIVIRIDAE |pagetype =Bugs }} <br> ====Hosts==== *Sheep *Grouse *Hares *Deer elk *Small...
{{unfinished}}
{{toplink
|linkpage =Viruses
|linktext =VIRUSES
|sublink1=Flaviviridae
|subtext1=FLAVIVIRIDAE
|pagetype =Bugs
}}
<br>
====Hosts====
*Sheep
*Grouse
*Hares
*Deer elk
*Small rodents
*Ticks (eg. ''Ixodes ricinus'')
*Man
====Pathogenesis====
*First phase:
**Pyrexia with virus in '''macrophages'''
**Recovery
*Second phase:
**Second replication in '''Purkinje cells''' of the cerebellum and '''motor nuclei''' of the brain stem
**Trembling, torticollis, and irregular gait
**In grouse: starvation
**In man: flu-like symptoms can be followed by coma, but recovery normal
====Epidemiology====
*Reservoir host: '''Ticks (''Ixodes ricinus'')'''
**Passed to host by '''saliva'''
**Virus can be spread '''between ticks''' when co-feeding on small rodents
*Spread mirrors seasonal tick activity
====Diagnosis====
*Clinical signs
*PM: virus isolation and histopathology of brain tissue
====Control====
*Sheep dipping in '''acaracides''' (vector control)
*'''Inactivated vaccines''' in late pregnancy can '''boost maternal antibody'''
**Lambs inoculated >4 months of age
*Human vaccination where at risk
{{toplink
|linkpage =Viruses
|linktext =VIRUSES
|sublink1=Flaviviridae
|subtext1=FLAVIVIRIDAE
|pagetype =Bugs
}}
<br>
====Hosts====
*Sheep
*Grouse
*Hares
*Deer elk
*Small rodents
*Ticks (eg. ''Ixodes ricinus'')
*Man
====Pathogenesis====
*First phase:
**Pyrexia with virus in '''macrophages'''
**Recovery
*Second phase:
**Second replication in '''Purkinje cells''' of the cerebellum and '''motor nuclei''' of the brain stem
**Trembling, torticollis, and irregular gait
**In grouse: starvation
**In man: flu-like symptoms can be followed by coma, but recovery normal
====Epidemiology====
*Reservoir host: '''Ticks (''Ixodes ricinus'')'''
**Passed to host by '''saliva'''
**Virus can be spread '''between ticks''' when co-feeding on small rodents
*Spread mirrors seasonal tick activity
====Diagnosis====
*Clinical signs
*PM: virus isolation and histopathology of brain tissue
====Control====
*Sheep dipping in '''acaracides''' (vector control)
*'''Inactivated vaccines''' in late pregnancy can '''boost maternal antibody'''
**Lambs inoculated >4 months of age
*Human vaccination where at risk