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→First Order Kinetic
Quantative Pharmacokinetic studies are used during drug development to standardise dosing regimens for a drug. The understanding of a drugs kinetics enables dosen adapatations for an individual, for example if an animal has renal failure. Knowing the '''half-life or T<sub>1/2</sub>''' of a drug is very useful in determining how long a drug will remain in the body. (Half-life is defined as the time taken for the plasma concentration of a drug to reduce by 50%.) The '''V<sub>d</sub>''' or Volume of Distribution of a drug helps determine the loading dose needed.
Quantative Pharmacokinetic studies are used during drug development to standardise dosing regimens for a drug. The understanding of a drugs kinetics enables dosen adapatations for an individual, for example if an animal has renal failure. Knowing the '''half-life or T<sub>1/2</sub>''' of a drug is very useful in determining how long a drug will remain in the body. (Half-life is defined as the time taken for the plasma concentration of a drug to reduce by 50%.) The '''V<sub>d</sub>''' or Volume of Distribution of a drug helps determine the loading dose needed.
===First Order Kinetic===
===First Order Kinetics===
This is when the half-life doesn't depend on dose administered.
This is when the half-life doesn't depend on dose administered.
Please insert appropriate drug clearance graphs
Please insert appropriate drug clearance graphs
===Zero Order===
===Zero Order===
This is when the elimination half-life depends on the dose administered.
This is when the elimination half-life depends on the dose administered.
Please insert appropriate drug clearance graphs
Please insert appropriate drug clearance graphs