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* Will kill nearly all anaerobic Gram-positive and negative bacteria.
* Will kill nearly all anaerobic Gram-positive and negative bacteria.
* Highly active against anaerobic protozoa, especially ''Treponema hyodysenteriae, Trichomonas foetus, Histomonas'' and ''Giardia''.
* Highly active against anaerobic protozoa, especially ''Treponema hyodysenteriae, [[Trichomonas foetus]], Histomonas'' and ''Giardia''.
They are small, lipid soluble molecules that are readily absorbed by the gastrointestinal tract. As such they have fantastic tissue penetration and can enter exclusive tissue such as the brain and the CSF. It is metabolised in the liver and 2/3 of the dose is then excreted in urine.
They are small, lipid soluble molecules that are readily absorbed by the gastrointestinal tract. As such they have fantastic tissue penetration and can enter exclusive tissue such as the brain and the CSF. It is metabolised in the liver and 2/3 of the dose is then excreted in urine.
==Side Effects and Contraindications==
==Side Effects and Contraindications==
* Acute CNS toxicity has been reported in dogs.
* Acute CNS toxicity has been reported in dogs.
* Use carefully and at low doses with pregnant animals because of possible mutagenic effects.
* Use carefully and at low doses with pregnant animals because of possible mutagenic effects.
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|Vetstream = [https://www.vetstream.com/equis/Content/Freeform/fre00358.asp Nitrofurans Nitroimidazoles Quinolones]}}