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The spleen is a major lymphoid and blood filtration organ and is located in the left cranial abdomen. It is responsible for storing and removing [[Erythrocytes - WikiBlood|erythrocytes]] from the blood as well as antigen surveillance of the blood and antibody production.

 

The spleen is a major lymphoid and blood filtration organ and is located in the left cranial abdomen. It is responsible for storing and removing [[Erythrocytes - WikiBlood|erythrocytes]] from the blood as well as antigen surveillance of the blood and antibody production. [[Image:LH_Canine_labelled_ventrodorsal_abdominal_organs_radiograph.jpg|150px]]

 

==Development==

==Development==

<p>The spleen develops in association with the digestive system in the dorsal mesogastrium, and as the [[Forestomach - Anatomy & Physiology|stomach]] rotates during development the spleen comes to occupy the left cranial abdomen. Haematopoietic cells in the spleen are derived from the AGM (aorta-gonad-mesonephros) and yolk sac and as the [[Primary Lymphoid Tissue - Anatomy & Physiology|primary lymphoid organs]] become established it becomes populated with [[Lymphocytes - WikiBlood#Types|T and B lymphocytes]].</p>

<p>The spleen develops in association with the digestive system in the dorsal mesogastrium, and as the [[Forestomach - Anatomy & Physiology|stomach]] rotates during development the spleen comes to occupy the left cranial abdomen. Haematopoietic cells in the spleen are derived from the AGM (aorta-gonad-mesonephros) and yolk sac and as the [[Primary Lymphoid Tissue - Anatomy & Physiology|primary lymphoid organs]] become established it becomes populated with [[Lymphocytes - WikiBlood#Types|T and B lymphocytes]].</p>