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Endocrine effects on the skin - Pathology (view source)
Revision as of 11:35, 29 October 2008
, 11:35, 29 October 2008→Specific changes associated with disease
**Microscopically: endocrine alopecia plus mucin within the dermis -> myxoedema (dermal thickening), acanthotic epidermal and follicular infundibular epithelium
**Microscopically: endocrine alopecia plus mucin within the dermis -> myxoedema (dermal thickening), acanthotic epidermal and follicular infundibular epithelium
**Secondary pyoderma is common
**Secondary pyoderma is common
*[[Adrenal Glands - Pathology#Adrenal_Hyperfunction|'''Hyperadrenocorticism''']]: [[Adrenal Glands - Pathology#Pathophysiology_2|Calcinosis cutis]] and dermal thinning.
*[[Adrenal Glands - Pathology#Adrenal_Hyperfunction|'''Hyperadrenocorticism''']]:
**Grossly: endocrine alopecia except on head and extremities, thin skin, comedones, easy bruising and poor wound healing, sometimes involves [Adrenal Glands - Pathology#Pathophysiology_2|calcinosis cutis]]
***In cats, skin is very easily torn
**Microscopically: epidermal, dermal and follicular atrophy, comedones, calcinosis cutis often with granulomatous inflammation and epidermal hyperplasia
*[[Pituitary Gland - Pathology#Pituitary_Hypofunction|'''GH deficiency''']]: Decreased dermal elastin and catagen follicles ('''Flame follicles''').
*[[Pituitary Gland - Pathology#Pituitary_Hypofunction|'''GH deficiency''']]: Decreased dermal elastin and catagen follicles ('''Flame follicles''').