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New page: {{unfinished}} {{toplink |linkpage =Viruses |linktext =VIRUSES |sublink1=Herpesviridae |subtext1=HERPESVIRUSES |pagetype =Bugs }} <br> ====Antigenicity==== *Two different viruses: **Infe...
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{{toplink
|linkpage =Viruses
|linktext =VIRUSES
|sublink1=Herpesviridae
|subtext1=HERPESVIRUSES
|pagetype =Bugs
}}
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====Antigenicity====
*Two different viruses:
**Infectious Bovine Rhinotracheitis (IBR): aerosol transfer
**Infectrious Pustular Vulvovaginitis (IPV): venereal transfer

====Pathogenesis====
IBR:
*Dypsnoea, anorexia
*Rhinotrachietis that can develop into bronchopneumonia
*Up to 75% mortality if concurrent with [[Bovine Virus Diarrhoea Virus|BVDV]], caused by meningo-encephalitis
IPV:
*Painful genital lesions
*Impaired reproductive performance
*Frequent micturition

====Diagnosis====
*Virus isolation and immunofluorescence

====Control====
*'''Vaccination''':
**Two '''live attenuated''' vaccines are available in the UK, one is temperature-sensitive
***Both given intranasally
***Neither protect against re-infection when given during clinical outbreak, but can lessen the severity of the disease
**'''Inactivated''' vaccines: intranasal/intramuscular administration
***gE deletion makes this a '''marker vaccine'''
***ELISA for gE deletion can enable culling of carrier animals
*IPV has mostly been made obsolete by AI
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