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New page: {{unfinished}} {{toplink |linkpage =Viruses |linktext =VIRUSES |sublink1=Herpesviridae |subtext1=HERPESVIRUSES |pagetype =Bugs }} <br> Also known as '''Aujeszky's Disease, Pseudorabies, ...
{{unfinished}}
{{toplink
|linkpage =Viruses
|linktext =VIRUSES
|sublink1=Herpesviridae
|subtext1=HERPESVIRUSES
|pagetype =Bugs
}}
<br>
Also known as '''Aujeszky's Disease, Pseudorabies, and Mad Itch'''
====Hosts====
*Pigs
*Cattle
*Horses
*Cats
*Dogs
Sheep
====Pathogenesis====
Sows:
*'''Aerosol''' transmission causes bronchopneumonia followed by viremia
*Sows will recover but some may abort
Piglets:
*Virus spreads to neurons, causing '''encephalitis''' with convulsions
*Many die within 2 days
Other animals:
*Air-borne virus can infect skin wounds
*Causes pruritis (mad itch) followed by encephalitis
====Epidemiology====
*Latent virus can be reactivated by mixing new stock in with old
====Diagnosis====
*'''ELISA''' for virus '''antibody'''
====Control====
*England: eradication in the 1980s by serotesting (by ELISA) and culling carriers
*'''Vaccines''' in Europe and Ireland
**gE-deleted '''marker vaccines''' stimulate cell-mediated immunity
{{toplink
|linkpage =Viruses
|linktext =VIRUSES
|sublink1=Herpesviridae
|subtext1=HERPESVIRUSES
|pagetype =Bugs
}}
<br>
Also known as '''Aujeszky's Disease, Pseudorabies, and Mad Itch'''
====Hosts====
*Pigs
*Cattle
*Horses
*Cats
*Dogs
Sheep
====Pathogenesis====
Sows:
*'''Aerosol''' transmission causes bronchopneumonia followed by viremia
*Sows will recover but some may abort
Piglets:
*Virus spreads to neurons, causing '''encephalitis''' with convulsions
*Many die within 2 days
Other animals:
*Air-borne virus can infect skin wounds
*Causes pruritis (mad itch) followed by encephalitis
====Epidemiology====
*Latent virus can be reactivated by mixing new stock in with old
====Diagnosis====
*'''ELISA''' for virus '''antibody'''
====Control====
*England: eradication in the 1980s by serotesting (by ELISA) and culling carriers
*'''Vaccines''' in Europe and Ireland
**gE-deleted '''marker vaccines''' stimulate cell-mediated immunity