− | Like all anti-infective agents resistance is starting to develop as a very serious problem within this set of drugs. This has been because the parasites experience high selection pressure, with the vast majority of the parasite population coming in contact with | + | Like all anti-infective agents resistance is starting to develop as a very serious problem within this set of drugs. This has been because the parasites experience high selection pressure, with the vast majority of the parasite population coming in contact with the toxicant. This leads to a higher prevelance of the resistant gene amongst the subsequent surviving generations. |