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| | + | =Introduction= |
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| | + | =Morphology= |
| | + | *Huge (up to 450nm), usually enveloped viruses, with a complex capsid symmetry |
| | + | *Up to 30 different structural proteins |
| | + | *Non-structural proteins: |
| | + | **Viral epidermal growth factor, which stimulates cell growth causing the raised edge of pustule |
| | + | **Viral tumor necrosis factor, which is non-functioning and acts as an anti-inflammatory by competing with TNF-<alpha> |
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| | + | =Virulence and Pathogenesis= |
| | + | *Once inside cell, proliferation then lysis, giving way to a characteristic pock with a necrotic center |
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| | + | =Epidemiology= |
| | + | *Spread quickly in unhygienic circumstances |
| | + | *Can survive for years in dust |
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| | + | =Types and Subtypes= |
| | + | * 6 Genera, all of which produce pox lesions |
| | + | *Subdivided based on external structure by EM |
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| | + | =Virus by Species= |
| | + | *[[Cow pox]], which also causes cat pox |
| | + | *Small pox (variola) |
| | + | *Orf |
| | + | *Seal pox |
| | + | *Pig pox |
| | + | *Sheep pox (exotic to EU) |
| | + | *Goat pox (exotic to EU) |
| | + | *Myxomatosis |
| | + | *Fowl pox |
| | + | *Pigeon pox |
| | + | *Canary pox |
| | + | *Ectromelia (mice) |
| | + | *Camel pox |
| | + | *Monkey pox |
| | + | *Lumpy skin disease |
| | + | *Red squirrel parapox |
| | + | *Red/Gray squirrel pox |
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| | + | =Diagnosis= |
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| | + | =Control= |
| | ==Introduction== | | ==Introduction== |
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