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, 21:40, 30 October 2008
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{{toplink
|linkpage =Viruses
|linktext =VIRUSES
|sublink1=Parvoviridae
|subtext1=PARVOVIRUSES
|pagetype =Bugs
}}
<br>
====Antigenicity====
*One serotype
====Hosts====
*Cats
*Mink
*Raccoons
*Pandas
====Pathogenesis====
*Also known as '''Feline Infectious Enteritis''' and '''Feline Panleukopenia'''
*Often fatal
*Pyrexia, severe enteritis (often bloody), dehydration, leukopenia, anemia
*Kittens <2 weeks show cerebellar hypoplasia
*Kittens more susceptible than cats
*Oral infection
*Initial replication in pharyngeal lymphoid tissue
*Viremia
*Virus targets rapidly dividing cells: lymph nodes, bone marrow, crypts of small intestine
====Epidemiology====
*Infection by '''direct contact''' and '''fomites'''
*Subclinical infections occur
*Virus excretion can be persistent
*'''Endemic worldwide'''
====Diagnosis====
*Clinical signs
*Hematology: leukopenia
*Can be confirmed by haemagglutination (HA) or ELISA using feces
====Control====
*'''Inactivated vaccines''' are available and essential for boarding
*Administered parenterally post-weaning to induce a systemic immune response to neutralize viremia
*Annual booster