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New page: {{unfinished}} {{toplink |linkpage =Viruses |linktext =VIRUSES |sublink1=Parvoviridae |subtext1=PARVOVIRUSES |pagetype =Bugs }} <br> ====Antigenicity==== *Single serotype ====Hosts==== ...
{{unfinished}}
{{toplink
|linkpage =Viruses
|linktext =VIRUSES
|sublink1=Parvoviridae
|subtext1=PARVOVIRUSES
|pagetype =Bugs
}}
<br>
====Antigenicity====
*Single serotype
====Hosts====
*Pigs
====Pathogenesis====
*Principal viral cause of '''SMEDI syndrome''': Stillbirths, Mummification, Embryonic Deaths, and Infertility
*Replicates in alimentary epithelium followed by viremia
*Often '''no clinical signs in breeding and growing stock'''
*'''Transplacental''' infection occurs in early pregnancy, with some (but not all) surviving piglets living as carriers
====Epidemiology====
*About 50% of UK pigs are antibody-positive
*Transfer is '''orofecal''' or via '''fomites'''
*Outbreaks occur as herd is developing immunity
*Congenitally infected piglets act as herd '''reservoir'''
====Diagnosis====
*'''Immunostaining''' of fetal tissues
*Virus isolation in cell culture
*HA on feces
*'''Rising antibody titres''' in paired serum sample by HAI
====Control====
*Inactivated vaccine (UK) or live attenuated (USA)
*Infected piglets should be culled
{{toplink
|linkpage =Viruses
|linktext =VIRUSES
|sublink1=Parvoviridae
|subtext1=PARVOVIRUSES
|pagetype =Bugs
}}
<br>
====Antigenicity====
*Single serotype
====Hosts====
*Pigs
====Pathogenesis====
*Principal viral cause of '''SMEDI syndrome''': Stillbirths, Mummification, Embryonic Deaths, and Infertility
*Replicates in alimentary epithelium followed by viremia
*Often '''no clinical signs in breeding and growing stock'''
*'''Transplacental''' infection occurs in early pregnancy, with some (but not all) surviving piglets living as carriers
====Epidemiology====
*About 50% of UK pigs are antibody-positive
*Transfer is '''orofecal''' or via '''fomites'''
*Outbreaks occur as herd is developing immunity
*Congenitally infected piglets act as herd '''reservoir'''
====Diagnosis====
*'''Immunostaining''' of fetal tissues
*Virus isolation in cell culture
*HA on feces
*'''Rising antibody titres''' in paired serum sample by HAI
====Control====
*Inactivated vaccine (UK) or live attenuated (USA)
*Infected piglets should be culled