3,320
edits
Changes
New page: {{review}} {{toplink |linkpage =WikiDrugs |linktext =WikiDrugs |sublink1 = Anthelmintic Drugs |subtext1 = Anthelmintic Drugs |pagetype = Drugs }} This is the only currently used drug in t...
{{review}}
{{toplink
|linkpage =WikiDrugs
|linktext =WikiDrugs
|sublink1 = Anthelmintic Drugs
|subtext1 = Anthelmintic Drugs
|pagetype = Drugs
}}
This is the only currently used drug in the pyrazinoisoquinolines. It has unsurpassed activity against [[cestodes]] and has activity against some [[trematodes]], these include schistosomes but not the liver flukes.
It works by causing an influx of Ca<sup>2+</sup> across the parasite tegument. This results in muscular spasms and the cestodes loose their position in the intestine and are moved away by peristalsis. This leads to the animals body attacking the cestodes weakened tegumental defence with antibodies, immune cells and lytic enzymes. The dead tapeworm is therefore mostly digested by the time it arrives in the faeces. Owner's of pets with tapeworms often feel that this drug doesn't work as they don't see any passed tapeworms. Where in fact the drug has worked but has left no visible evidence to the owner of it's working.
{{toplink
|linkpage =WikiDrugs
|linktext =WikiDrugs
|sublink1 = Anthelmintic Drugs
|subtext1 = Anthelmintic Drugs
|pagetype = Drugs
}}
This is the only currently used drug in the pyrazinoisoquinolines. It has unsurpassed activity against [[cestodes]] and has activity against some [[trematodes]], these include schistosomes but not the liver flukes.
It works by causing an influx of Ca<sup>2+</sup> across the parasite tegument. This results in muscular spasms and the cestodes loose their position in the intestine and are moved away by peristalsis. This leads to the animals body attacking the cestodes weakened tegumental defence with antibodies, immune cells and lytic enzymes. The dead tapeworm is therefore mostly digested by the time it arrives in the faeces. Owner's of pets with tapeworms often feel that this drug doesn't work as they don't see any passed tapeworms. Where in fact the drug has worked but has left no visible evidence to the owner of it's working.