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==Drugs Increasing Smooth Muscle Contractility==
==Drugs Increasing Smooth Muscle Contractility==
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These drugs are used for conditions that are associated with '''hypomotility''', such as megacolon, oesophageal reflux, atony and ileus.
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'''Drugs Acting on 5-HT<sub>4</sub> Receptors'''
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* An examples is '''metoclopramide''' that is an agonist at serotonin and dopamine receptors, this results in an increased release of acetylcholine and so increases gut motility.
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'''Muscarinic Receptor Agonists'''
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* Examples are '''carbachol''' and '''bethanecol'''. They should be used with slight caution as their resultant contractions can be painful.
==Laxatives and Purgatives==
==Laxatives and Purgatives==