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→Pathogenesis
====Pathogenesis====
====Pathogenesis====
*Transfer occurs through blood from viremic animals via biting midges ('''Culicodes spp.''')
*Transfer occurs through blood from viremic animals via biting midges ('''Culicoides spp.''')
*Replication in haematopoietic and endothelial cells of blood vessels
*Replication in haematopoietic and endothelial cells of blood vessels
*Clinical signs vary between species, with sheep most severely affected
*Clinical signs vary between species, with sheep most severely affected