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| + | ==Toxoplasma== |
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| + | *1 major pathogenic species called ''Toxoplasma gondii'' |
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| + | *Causes disease in a wide range of animal species including humans |
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| + | *Important cause of abortion in sheep |
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| + | *Zoonotic |
| + | **Can cause abortion |
| + | **Can cause congenitally aquired defects |
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| + | *Forms a sporulated oocyst which is only 10μm |
| + | **Contains 2 sporocysts with 4 sporozoites |
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| + | *Transmission through ingesting the intermediate host or via the faecal-oral route |
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| + | '''Life Cycle''' |
| + | *Complex |
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| + | *Usually indirect |
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| + | *Gametogeny (sexual stage) is host specific for felids |
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| + | *Any warm blooded animal can act as a facultative intermediate host |
| + | **Asexual reproduction occurs in the intermediate host forming tissue cysts |
| + | **Intermediate host swallows sporulated oocysts or tissue cysts |
| + | **Can be transferred between intermediate hosts by carnivorism |
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| Toxoplasma can cause [[Pancreas Inflammatory - Pathology#Acute haemorrhagic pancreatitis|acute interstitial pancreatitis]] in systemic toxoplasmosis | | Toxoplasma can cause [[Pancreas Inflammatory - Pathology#Acute haemorrhagic pancreatitis|acute interstitial pancreatitis]] in systemic toxoplasmosis |
| *''T. gondii'' in [[Respiratory Parasitic Infections - Pathology#Toxoplasmosis|pneumonia]] | | *''T. gondii'' in [[Respiratory Parasitic Infections - Pathology#Toxoplasmosis|pneumonia]] |
| *''Toxoplasma gondii'', ''Sarcocystis'' and ''Neospora caninum'' in [[Muscles Inflammatory - Pathology#Protozoa|myositis]] | | *''Toxoplasma gondii'', ''Sarcocystis'' and ''Neospora caninum'' in [[Muscles Inflammatory - Pathology#Protozoa|myositis]] |
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| + | ==Sarcocystis== |
| + | *Most infections are asymptomatic |
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| + | *Heavy infections are causes of chronic wasting in large animals, hide sondemnation and downgrading of carcasses |
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| + | *''Sarcocystis'' should be differentiated from other tissue-cyst forming coccidia |
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| + | *There are many species of ''Sarcocystis'' |
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| + | *Sporulated oocyst has 2 sporocysts containing 4 sporozoites |
| + | **Naked oocyst usually seen in faeces as the oocyst wall is very delicate |
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| + | *Indirect life cycle |
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| + | *Life cycle alternates between the final and the obligatory intermediate host |
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| + | *Only one final and one intermediate host |
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| + | ==Neospora== |
| + | *2 main species |
| + | **''Neospora caninum'' in the dog |
| + | **''Neospora hughesi'' in the horse |
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| + | *Sporulated oocysts measuring just 10μm |
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| + | *Oocyst contains 2 sporocysts with 4 sporozoites |
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| + | *Life cycle similar to ''Toxoplasma gondii'' |
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| + | *Limited range of warm-blooded intermediate hosts |
| + | **Asexual reproduction occurs in intermediate host forming tissue cysts |
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| + | *Host range of sexual stage is unknown for ''N.caninum'' |
| + | **Intermediate host for ''N.hughesi'' is the horse, but the definitive host is unknown |
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| + | *Route of transmission not fully understood |