Changes

*Few flukicides kill all parasitic developmental stages

*Few flukicides kill all parasitic developmental stages

*Not all products, therefore, are suitable for controlling acute outbreaks

*Not all products, therefore, are suitable for controlling acute outbreaks

*The anthelmintic with the broadest spectrum of activity against immature and adult ''F. hepatica'' is '''Triclabendazole''' *Triclabendazole-resistant ''F. hepatica'' populations are beginning to emerge

*The anthelmintic with the broadest spectrum of activity against immature and adult ''F. hepatica'' is '''Triclabendazole'''

<nb>*Triclabendazole-resistant ''F. hepatica'' populations are beginning to emerge

*The more potent products tend to be the most expensive

*The more potent products tend to be the most expensive

*Many flukicides bind to plasma protein and have long plasma half-lives

*Many flukicides bind to plasma protein and have long plasma half-lives