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===Inverse Agonists===
 
===Inverse Agonists===
   −
These are agonists that bind to receptors that are continuely activated (even if no ligand is present) and result in the reduction of the level of activation. They therfore have a negative efficacy.
+
These are agonists that bind to receptors that are continuely activated (even if no ligand is present) and result in the reduction of the level of activation. They therefore have a negative efficacy.
 
      
===Effector Linkage Mechanisms===
 
===Effector Linkage Mechanisms===
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