Changes

==Pharmacokinetics==

==Pharmacokinetics==

At room temperature, halothane is a liquid and so requires a [[Vaporisers|vaporiser]] before it reaches the patient. It needs to be stored in a darkened bottle due to ultraviolet degradation. The '''blood:gas partition coefficient''' is moderately low meaning that it is relatively insoluble in blood. This results in relatively rapid induction, recovery and depth change. The MAC for halothane is approximately ''0.9%'', meaning it is highly potent. Halothane undergoes a degree of hepatic metabolism by the cytochrome P450 system found in hepatocytes.  

At room temperature, halothane is a liquid and so requires a [[Vaporisers|vaporiser]] before it reaches the patient. It needs to be stored in a darkened bottle due to ultraviolet degradation. It contains a preservative, Thymol, which can accumulate within the vaporiser The '''blood:gas partition coefficient''' is moderately low meaning that it is relatively insoluble in blood. This results in relatively rapid induction, recovery and depth change. The MAC for halothane is approximately ''0.9%'', meaning it is highly potent. Halothane undergoes a degree of hepatic metabolism by the cytochrome P450 system found in hepatocytes.  

==Adverse Effects==

==Adverse Effects==