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→Epizootic Lymphangitis
*Occurs in Europe, Africa and Asia
*Occurs in Europe, Africa and Asia
**Eradicated from the UK but is still under the notifiable Diseases of Animals Act
*Chronic disease
*Chronic disease
*Highly contageous
**Spread by direct contact or indirect, e.g. through infected grooming equipment, [[Biting Flies|biting flies]]
*Once established in a population it is very difficult to eradicate
**Long incubation peroid
**New cases can develop weeks or months after the infection appears to have been eradicated
*Affects the [[Lymph Nodes - Anatomy & Physiology|lymph nodes]], [[Lymphatic Vessels - Anatomy & Physiology|lymph vessels]] and [[Skin - Anatomy & Physiology|skin]]
*Affects the [[Lymph Nodes - Anatomy & Physiology|lymph nodes]], [[Lymphatic Vessels - Anatomy & Physiology|lymph vessels]] and [[Skin - Anatomy & Physiology|skin]]
**Dissemination occurs
**Dissemination occurs
**Pulmonary disease can occur
**Pulmonary disease can occur
**Ulcers rupture, discharging blood-stained pus for several weeks
*Oval or pear shaped cells
*Oval or pear shaped cells
**Growth is slow, taking up to 8 weeks
**Growth is slow, taking up to 8 weeks
**At room temperature, thick-walled chlamydospores can be seen
**At room temperature, thick-walled chlamydospores can be seen
**Orgnaisms can usually be seen in swollen [[Leukocytes - WikiBlood|leucocytes]]
*Can be stained using Gram, Giemsa, H & E and 10% Methylene Blue followed by Carbol Fuchsin
*Enzyme-linked immunosorbant assay can be used to detect the fungi
*Enzyme-linked immunosorbant assay can be used to detect the fungi
*Life-long immunity follows recovery from infection
*Treatment included potassium iodide, [[Antifungal Drugs#Polyene Antifungals|hamycin]] and [[Antifungal Drugs#Polyene Antifungals|Amphotericin B]]
*Treatment included potassium iodide, [[Antifungal Drugs#Polyene Antifungals|hamycin]] and [[Antifungal Drugs#Polyene Antifungals|Amphotericin B]]
**Vaccination has also proven to be effective
**Injection of hyperimmune serum around skin lesions has been proven to be effective
==Eumycotic Mycetoma==
==Eumycotic Mycetoma==