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==Signalment==
==Signalment==
More common in cats than in dogs. Cats of all breeds and ages can be affected, but often young to middle-aged cats. Male cats are more at risk.
More common in cats than in dogs. Cats of all breeds and ages can be affected, but often young to middle-aged cats. Male cats are more at risk.
==Description==
==Description==
Neutrophilic cholangitis/cholangiohepatitis results from ascending bacterial infection from the small intestines. ''Escherichia coli'', ''Staphylococcus spp.'', ''Streptococcus spp.'', ''Clostridium spp.'', ''Bacillus spp.'', ''Actinomyces spp.'', ''Bacteroides spp.'' and occasionally ''Salmonella spp.'' have been isolated. Concurrent biliary tract disease are common in cats, especially pancreatitis and inflammatory bowel disease. Other predisposing factors include bile duct obstruction, cholelithiasis, cholecystitis.
Neutrophilic cholangitis/cholangiohepatitis results from ascending bacterial infection from the small intestines. ''Escherichia coli'', ''Staphylococcus spp.'', ''Streptococcus spp.'', ''Clostridium spp.'', ''Bacillus spp.'', ''Actinomyces spp.'', ''Bacteroides spp.'' and occasionally ''Salmonella spp.'' have been isolated. Concurrent biliary tract disease are common in cats, especially pancreatitis and inflammatory bowel disease. Other predisposing factors include bile duct obstruction, cholelithiasis, cholecystitis.
==Diagnosis==
==Diagnosis==
===Clinical Signs===
===Clinical Signs===
Acute presentation with pyrexia, abdominal pain, lethargy, jaundice.
Acute presentation with pyrexia, abdominal pain, lethargy, jaundice.
===Haematology & Biochemistry===
===Haematology & Biochemistry===
Increased segmented and band neutrophils.
Increased segmented and band neutrophils.
Increased ALT and total bilirubin concentration
Increased ALT and total bilirubin concentration
===Imaging===
===Imaging===
A coarse or nodular texture to the liver on ultrasonography. More chronic cases may have dilation of the biliary tract.
A coarse or nodular texture to the liver on ultrasonography. More chronic cases may have dilation of the biliary tract.
===Cytology and Culture===
===Cytology and Culture===
*Ursodeoxycholic acid at 15 mg/kg q24hours may be given due to its choleretic, which promotes increased fluidity of biliary secretions to treat or prevent sludging, and hepatoprotective (anti-inflammatory, immunomodulatory and antifibrotic effects) properties.
*Ursodeoxycholic acid at 15 mg/kg q24hours may be given due to its choleretic, which promotes increased fluidity of biliary secretions to treat or prevent sludging, and hepatoprotective (anti-inflammatory, immunomodulatory and antifibrotic effects) properties.
*A high protein diet rather than a protein-restricted diet is more appropriate for feeding anorexic cats to prevent the development of hepatic lipidosis
*A high protein diet rather than a protein-restricted diet is more appropriate for feeding anorexic cats to prevent the development of hepatic lipidosis
==Prognosis==
==Prognosis==
Good provided the cats are treated early and appropriately.
Good provided the cats are treated early and appropriately.