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EPI (view source)

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[[Pancreatic Conditions|Exocrine Pancreatic Insufficiency]]

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<big><center>[[Pancreas Developmental - Pathology|'''BACK TO PANCREAS - DEVELOPMENTAL''']]</center></big>

<big><center>[[Pancreas Degenerative - Pathology|'''BACK TO PANCREAS - DEGENERATIVE''']]</center></big>

<big><center>[[Pancreas Inflammatory - Pathology|'''BACK TO PANCREAS - INFLAMMATORY''']]</center></big>

<big><center>[[Pancreas Hyperplastic and Neoplastic - Pathology|'''BACK TO PANCREAS - HYPERPLASTIC AND NEOPLASTIC''']]</center></big>

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*'''Exocrine pancreatic insufficiency (EPI)''' is a syndrome caused by insufficient synthesis and secretion of digestive enzymes by the exocrine portion of the pancreas

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*Leading to insufficient activity of digestive enzymes in the lumen of the small intestine

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*Pancreas has considerable functional reserve, large proportion needs to be non-functional to show signs of EPI

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*Most common in dog - usually associated with [[Pancreas Degenerative - Pathology|pancreatic atrophy]] or [[Pancreas Inflammatory - Pathology#Chronic Pancreatitis|chronic pancreatitis]]

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*Occurs occasionally in other species, esp. calves with [[Pancreas Developmental - Pathology#Pancreatic hypoplasia|pancreatic hypoplasia]] and in cats

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*'''Clinical signs'''

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**Steatorrhoea

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**Diarrhoea

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**Weight loss

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**Increased appetite

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*In contrast, '''horses''' with very little pancreatic tissue develop '''hypoinsulinism''' but rarely EPI

Dmassey

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EPI (view source)

Revision as of 11:37, 7 August 2009

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