210
edits
Changes
Jump to navigation
Jump to search
no edit summary
==Signalment==
==Signalment==
Historically reported most frequently in cats but now also in dogs.
* Historically reported most frequently in cats but now also in dogs
* Usually seen in younger dogs
* No sex predisposition
* In a recent study of dogs confirmed as having dysautonomia those raised and housed in rural environments appeared to be at greater risk (56/65 dogs) for dysautonomia than dogs from the city
* Labrador Retrievers may have a breed predisposition
==Description==
==Description==
====Contrast Radiography====
====Contrast Radiography====
Oesophageal hypomotility may be evident on barium contrast study.
Oesophageal hypomotility may be evident on barium contrast study.
===Histological Findings===
Chromatolytic degeneration in autonomic ganglia, spinal cord intermediate grey columns and some sympathetic axons.
===Pharmalogical Testing===
* Topical ocular administration of dilute pilocarpine - miosis implies a postive result. However, not all dogs will respond. Response is dependent on damage to the postganglionic parasympathetic neuron that results in supersensitivity of the iris muscle dogs.
* IV or SC administration of atropine (a parasympatholytic)
* ID administration of histamine - the wheal and flare response may be dampened in those with dysautonomia
==Differential Diagnosis==
==Differential Diagnosis==