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| ==Description== | | ==Description== |
− | '''Lymphocytic - plasmacytic enteritis''' (LPE) is the most common form of [[Inflammatory Bowel Disease - WikiClinical|Inflammatory Bowel Disease]]. As its name suggests, the predominant cell type in the intestinal mucosa is lymphocytes and plasma cells. Enteric parasites, bacteria in dogs and ''Toxoplasma'' in cats have been reported to associated with LPE. This disorder in cats have also been shown to associate with concurrent disease of the pancreas and liver such as pancreatitis, cholangitis and hepatic lipidosis. | + | '''Lymphocytic - plasmacytic enteritis''' (LPE) is the most common form of [[Inflammatory Bowel Disease - WikiClinical|Inflammatory Bowel Disease]]. As its name suggests, the predominant cell type in the intestinal mucosa is '''lymphocytes''' and '''plasma cells'''. Enteric parasites, bacteria in dogs and ''Toxoplasma'' in cats have been reported to associated with LPE. This disorder in cats have also been shown to associate with concurrent disease of the pancreas and liver such as pancreatitis, cholangitis and hepatic lipidosis. This disease in animal has been compared to the human dsease. LPE is believed to be caused by an abnormal MALT response to luminal bacterial, dietary or self-antigens. |
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− | The small intestines is affected to a variable degree of serverity. It has also been known to affect other parts of the gastrointestinal tract such as the stomach and the colon. In severely affected animals, a protein-losing enteropathy will result. | + | The small intestines is affected to a variable degree of serverity. It has also been known to affect other parts of the gastrointestinal tract such as the stomach and the colon. In severely affected animals, this will result in a protein-losing enteropathy (PLE). |
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− | Produces chronic diarrhoea with lymphocytic or plasma cell (rather than macrophage) infiltration of the lamina propria. Produces a severe [[Intestines Protein-Losing Diseases - Pathology#Protein-Losing Enteropathy (PLE)|protein losing enteropathy]]. Sometimes eosinophil infiltration is quite marked. Has a hereditary basis in the Basenji
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| ==Diagnosis== | | ==Diagnosis== |
| ===Clinical Signs=== | | ===Clinical Signs=== |
− | | + | *Small intestinal diarrhoea. |
| + | *Weight loss |
| + | *Protein - losing enteropathy in severe cases |
| + | *Chronic vomiting (common in cats, sometimes in dogs) |
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