* Usually non-specific. The following are frequently observed in dogs:
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** Mild non-regenerative anaemia - cause idiopathic, however, anaemia of chronic disease, inflammation, red blood cell sequestration and iron deficiency may play roles
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** Leukocytosis - resulting from the associated inflammation and necrosis with large liver masses
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** Thrombocytosis - potential causes include production of thrombopoietin as a parneoplastic syndrome, iron deficiency, inflammatory cytokines and anaemia
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* Elevated hepatic enzymes - likely due to hepatocellular damage or biliary stasis though the level of enzyme increase is not proportional to severity of liver damage