Changes

==Signalment and Description==

==Signalment and Description==

===Hepatocellular Tumours (Hepatocellular carcinomas (HCC) and Hepatomas)===

===Hepatocellular Tumours ([[Liver Proliferative - Pathology #Hepatocytic|Hepatocellular carcinomas]] (HCC) and [[Liver Proliferative - Pathology #Hepatocytic|Hepatomas]])===

* HCC occurs more frequently in dogs and hepatomas more commonly in cats. They are the most common primary liver tumour in dogs and the second most common in cats.  

* HCC occurs more frequently in dogs and hepatomas more commonly in cats. They are the most common primary liver tumour in dogs and the second most common in cats.  

* Male dogs over 10 years old are the most frequently affected by HCC and Miniature schnauzers may have a breed predisposition.

* Male dogs over 10 years old are the most frequently affected by HCC and Miniature schnauzers may have a breed predisposition.

* Metastatic rate for dogs with massive HCC: 0-37%

* Metastatic rate for dogs with massive HCC: 0-37%

* Metastatic rate for dogs with nodular and diffuse HCC: 93-100%

* Metastatic rate for dogs with nodular and diffuse HCC: 93-100%

* Hepatomas are usually incidental findings and non-significant

* [[Liver Proliferative - Pathology #Hepatocytic|Hepatomas]]) are usually incidental findings and non-significant

===Cholangiocellular Tumours (Bile duct carcinomas and adenomas)===

===Cholangiocellular Tumours (Bile duct carcinomas and adenomas)===

* Primary tumours are aggressive and often affect more than one liver lobe and metastasise most frequently to the regional lymph nodes, the lungs and peritoneum.  

* Primary tumours are aggressive and often affect more than one liver lobe and metastasise most frequently to the regional lymph nodes, the lungs and peritoneum.  

===Sarcomas (Haemangiosarcoma (HSA), Leiomyosarcoma, Fibrosarcoma)===

===Sarcomas ([[Liver Proliferative - Pathology #Haemangiosarcoma|Haemangiosarcoma]] (HSA), Leiomyosarcoma, Fibrosarcoma)===

* HSA is the most common hepatic sarcoma in cats

* HSA is the most common hepatic sarcoma in cats

* Leiomyosarcoma is the most common hepatic sarcoma in dogs

* Leiomyosarcoma is the most common hepatic sarcoma in dogs

==Treatment==

==Treatment==

===Surgery===

===Surgery===

Surgical excision is adivsed for hepatic adenomas, bile duct adenomas and massive hepatocellular carcinomas. Nodulectomy or lobectomy can be used for focal tumours of one or more lobes. Diffuse tumours and widespread nodular disease carry a worse prognosis.

Surgical excision is advised for hepatic adenomas, bile duct adenomas and massive [[Liver Proliferative - Pathology #Hepatocytic|hepatocellular carcinomas]]. Nodulectomy or lobectomy can be used for focal tumours of one or more lobes. Diffuse tumours and widespread nodular disease carry a worse prognosis.

===Chemotherpay===

===Chemotherpay===

Not currently recommended for primary hepatic neoplasia. Some metastatic sarcomas, for example haemangiosarcomas, may show some response.

Not currently recommended for primary hepatic neoplasia. Some metastatic sarcomas, for example [[Liver Proliferative - Pathology #Haemangiosarcoma|haemangiosarcomas]], may show some response.

===Radiotherapy===

===Radiotherapy===

==Prognosis==

==Prognosis==

The mean survival time for massive hepatocellular cacinomas following surgery is approximately 1 year. Otherwise the prognosis is poor for other malignant and metastatic tumours. If successfully excised the prognosis for benign tumours is good.

The mean survival time for massive [[Liver Proliferative - Pathology #Hepatocytic|hepatocellular carcinomas]] following surgery is approximately 1 year. Otherwise the prognosis is poor for other malignant and metastatic tumours. If successfully excised the prognosis for benign tumours is good.