− | Aetiology is idiopathic. Adenomas, although they do not metastasise and are frequently small and focal they can compress the surrounding pancreas. Carcinomas are aggressive with local invasion of the stomach or duodenum and metastasis to the liver, regional lymph nodes (hepatic and splenic), lungs, periotoneal surface and other abdominal organs occurring prior to a diagnosis being reached. Other complications include blockage of the common bile duct and exocrine pancreatic insufficiency. Pancreatitis can also occur where pancreatic atrophy results in tumour necrosis and an inflammatory response. | + | Aetiology is idiopathic. Adenomas, although they do not metastasise and are frequently small and focal they can compress the surrounding pancreas. Carcinomas are aggressive with local invasion of the stomach or duodenum and metastasis to the liver, regional lymph nodes (hepatic and splenic), lungs, periotoneal surface and other abdominal organs usually occurring prior to a diagnosis being reached. Other complications include blockage of the common bile duct and exocrine pancreatic insufficiency. Pancreatitis can also occur where pancreatic atrophy results in tumour necrosis and an inflammatory response. |