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* If semen is deposited in the cranial vagina, capacitation may begin as sperm ascend the [[Female_Reproductive_Tract_-The_Cervix_-_Anatomy_%26_Physiology|cervix]].
 
* If semen is deposited in the cranial vagina, capacitation may begin as sperm ascend the [[Female_Reproductive_Tract_-The_Cervix_-_Anatomy_%26_Physiology|cervix]].
 
* If semen is deposited in the caudal [[Female_Reproductive_Tract_-The_Cervix_-_Anatomy_%26_Physiology|cervix]] (mare) or mid-[[Female_Reproductive_Tract_-The_Cervix_-_Anatomy_%26_Physiology|cervix]] (sow) and immediately enters the [[Female_Reproductive_Tract_-The_Uterus_-_Anatomy_%26_Physiology|uterus]], capacitation is initiated in the [[Female_Reproductive_Tract_-The_Uterus_-_Anatomy_%26_Physiology|uterus]] and completed in the isthmus of the [[Female_Reproductive_Tract_-The_Oviduct_-_Anatomy_%26_Physiology|oviduct]].
 
* If semen is deposited in the caudal [[Female_Reproductive_Tract_-The_Cervix_-_Anatomy_%26_Physiology|cervix]] (mare) or mid-[[Female_Reproductive_Tract_-The_Cervix_-_Anatomy_%26_Physiology|cervix]] (sow) and immediately enters the [[Female_Reproductive_Tract_-The_Uterus_-_Anatomy_%26_Physiology|uterus]], capacitation is initiated in the [[Female_Reproductive_Tract_-The_Uterus_-_Anatomy_%26_Physiology|uterus]] and completed in the isthmus of the [[Female_Reproductive_Tract_-The_Oviduct_-_Anatomy_%26_Physiology|oviduct]].
* During Capacitation, the plasma membrane of the sperm undergoes marked biochemical changes.
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* During capacitation, the plasma membrane of the sperm undergoes marked biochemical changes.
 
* During mixing of sperm with seminal plasma, epididymal sperm become coated in seminal plasma proteins.  These are stripped by the female tract environment.  These proteins were the decapacitating agents that were rendering the sperm incapable of fertilization.
 
* During mixing of sperm with seminal plasma, epididymal sperm become coated in seminal plasma proteins.  These are stripped by the female tract environment.  These proteins were the decapacitating agents that were rendering the sperm incapable of fertilization.
 
* Once the plasma proteins have been stripped, the portions of molecules that can bind to the zona pellucida of the oocyte are exposed.
 
* Once the plasma proteins have been stripped, the portions of molecules that can bind to the zona pellucida of the oocyte are exposed.
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