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*Grossly:
 
*Grossly:
 
**Red and swollen extremities
 
**Red and swollen extremities
**[[General Pathology - Necrosis#Dry Gangrene|Dry gangrene]] may develop on pinnae and tail
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**[[Necrosis - Pathology#Dry Gangrene|Dry gangrene]] may develop on pinnae and tail
 
===Fescue poisoning===
 
===Fescue poisoning===
 
*Caused by excessive consumption of ''Festuca arudinacea''
 
*Caused by excessive consumption of ''Festuca arudinacea''
 
*Clinical signs develop about two weeks after consumption
 
*Clinical signs develop about two weeks after consumption
 
*Grossly:
 
*Grossly:
**[[General Pathology - Necrosis#Dry Gangrene|Dry gangrene]] of extremities
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**[[Necrosis - Pathology#Dry Gangrene|Dry gangrene]] of extremities
 
**Similar to [[Skin Environmental - Pathology#Ergot poisoning|ergot poisoning]]
 
**Similar to [[Skin Environmental - Pathology#Ergot poisoning|ergot poisoning]]
 
===Selenium poisoning===
 
===Selenium poisoning===
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*Lesions may occur in wet or hypoglycaemic neonates or animals recently moved from warm to cold environment
 
*Lesions may occur in wet or hypoglycaemic neonates or animals recently moved from warm to cold environment
 
*Areas affected are extremities
 
*Areas affected are extremities
*Lesions consist of [[General Pathology - Necrosis#Gangrene|gangrene]] and necrotic tissue
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*Lesions consist of [[Necrosis - Pathology#Gangrene|gangrene]] and necrotic tissue
    
===High temperature damage===
 
===High temperature damage===
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***Vesicles
 
***Vesicles
 
**Microscopically:
 
**Microscopically:
***[[General Pathology - Necrosis#Coagulation Necrosis|Coagulation necrosis]] of epidermis
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***[[Necrosis - Pathology#Coagulation Necrosis|Coagulation necrosis]] of epidermis
 
***Subepidermal vesiculation
 
***Subepidermal vesiculation
 
***Necrosis of adnexa
 
***Necrosis of adnexa