Changes

The pathophysiology of PSS relates to the shunting of blood directly from the systemic circulation, resulting in hyperammonaemia and [[Hepatic Encephalopathy]].

The pathophysiology of PSS relates to the shunting of blood directly from the systemic circulation, resulting in hyperammonaemia and [[Hepatic Encephalopathy]].

==Diagnosis==

==Diagnosis==

**An increase in ammonium concentration in the blood decreases the ability of enzymes to convert [[Urate Metabolism - Pathology|uric acid]] to allantoin, thereby resulting in urate urolithiasis.

**An increase in ammonium concentration in the blood decreases the ability of enzymes to convert [[Urate Metabolism - Pathology|uric acid]] to allantoin, thereby resulting in urate urolithiasis.

*Intermittent [[Stomach and Abomasum Consequences of Gastric Disease - Pathology|vomiting]] or [[Intestine Diarrhoea - Pathology|diarrhoea]]

*Intermittent [[Stomach and Abomasum Consequences of Gastric Disease - Pathology|vomiting]] or [[Intestine Diarrhoea - Pathology|diarrhoea]]

===Laboratory Tests===

===Laboratory Tests===

*Increased postprandial ± preprandial [[Liver - Anatomy & Physiology #Bile Acids|bile acids]]

*Increased postprandial ± preprandial [[Liver - Anatomy & Physiology #Bile Acids|bile acids]]

*Increased ammonia levels

*Increased ammonia levels

===Diagnostic Imaging===

===Diagnostic Imaging===