Changes

Buprenorphine is a Schedule 3 controlled drug used for the relief of moderate pain. It is licensed for veterinary used and may be given i/v, i/m, s/c or p/o. Its actions last 6-8 hours.

Buprenorphine is a Schedule 3 controlled drug used for the relief of moderate pain. It is licensed for veterinary used and may be given i/v, i/m, s/c or p/o. Its actions last 6-8 hours.

Buprenorphine is a partial OP3 agonist/antagonist. This gives it a bell-shaped dose response curve, with large experimental doses actually causing opioid receptor antagonism. Buprenophine may therefore cause partial reversal of administration of full OP3 agonists such as [[#Morphine|morphine]], [[#Methadone|methadone]], [[#Pethidine|pethidine]] or [[#Fentanyl|fentanyl]].

Buprenorphine is a partial OP3 agonist. This gives it a bell-shaped dose response curve, with large experimental doses actually causing opioid receptor antagonism. Buprenophine may therefore cause partial reversal of administration of full OP3 agonists such as [[#Morphine|morphine]], [[#Methadone|methadone]], [[#Pethidine|pethidine]] or [[#Fentanyl|fentanyl]].

===Butorphanol===

===Butorphanol===