− | At room temperature, halothane is a liquid and so requires a [[Vaporisers|vaporiser]] before it reaches the patient. It needs to be stored in a darkened bottle due to ultraviolet degradation. It contains a preservative, Thymol, which can accumulate within the vaporiser The '''blood:gas partition coefficient''' is moderately low meaning that it is relatively insoluble in blood. This results in relatively rapid induction, recovery and depth change. The [[Inhalation Agents#General Pharmacokinetics#Minimum Alveolar Concentration|'''MAC''']] for halothane is approximately ''0.9%'', meaning it is highly potent. Halothane undergoes a degree of hepatic metabolism by the cytochrome P450 system found in hepatocytes. | + | At room temperature, halothane is a liquid and so requires a [[Vaporisers|vaporiser]] before it reaches the patient. It needs to be stored in a darkened bottle due to ultraviolet degradation. It contains a preservative, Thymol, which can accumulate within the vaporiser The '''blood:gas partition coefficient''' is moderately low meaning that it is relatively insoluble in blood. This results in relatively rapid induction, recovery and depth change. The [[Inhalation Agents#General Pharmacokinetics#Minimum Alveolar Concentration|'''MAC''']] for halothane is approximately ''0.9%'' in dogs and ''1.1%'' in cats, meaning it is highly potent. Halothane undergoes a degree of hepatic metabolism by the cytochrome P450 system found in hepatocytes. |