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→Pathogenesis
====Pathogenesis====
====Pathogenesis====
*Principal viral cause of '''SMEDI syndrome''': Stillbirths, Mummification, Embryonic Deaths, and Infertility
*Principal viral cause of '''SMEDI syndrome''': Stillbirths, Mummification, Embryonic Deaths, and Infertility
*Replicates in gastro-intestinal epithelium followed by viremia
*Replicates in gastrointestinal epithelium followed by viremia
*Often '''no clinical signs in breeding and growing stock'''
*Often '''no clinical signs in breeding and growing stock'''
*'''Transplacental''' infection occurs in early pregnancy, with some (but not all) surviving piglets living as carriers
*'''Transplacental''' infection occurs in early pregnancy, with some (but not all) surviving piglets living as carriers