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Morantel (view source)

Revision as of 21:31, 29 September 2009

646 bytes removed ,  21:31, 29 September 2009
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These belong to the tetrahydropyrimidines class of drugs and a known by farmers as yellow drenches. The product code in the UK is '''2-LM'''.
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It belongs to the tetrahydropyrimidines class of drugs which are known by farmers as yellow drenches. The product code in the UK is '''2-LM'''.
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==Levamisole==
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* This is one of the most widely used anthelmintics and can be given orally, by injection or as a pour on.
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* It is active against adult '''[[Nematodes]]''', but has limited action against the larval stages, especially the hypobiotic phase.
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* It is a cholinergic agonist at neural and neuromuscular junctions causing a '''spastic paralysis''' of the nematode. The nematodes succumb rapidly to it.
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* It is rapidly absorbed and excreted and its potency is related to its peak plasma concentrations. Therefore pour-on products need a higher dose, as they are absorbed more slowly, to reach the same plasma concentrations.
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==Morantel==
   
* This works in a similar fashion to levamisole but isn't absorbed by the alimentary tract.
 
* This works in a similar fashion to levamisole but isn't absorbed by the alimentary tract.
 
* It has limited activity against larval forms and so has little uses.
 
* It has limited activity against larval forms and so has little uses.
 
* Morantel is used in some rumenal boluses.
 
* Morantel is used in some rumenal boluses.
 
* Pyrantel, a similar product, is used for against equine [[cestodes]].
 
* Pyrantel, a similar product, is used for against equine [[cestodes]].
Amazonian
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