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Adrenal Glands - Pathology (view source)
Revision as of 12:59, 24 November 2009
, 12:59, 24 November 2009→Treatment
*'''Mitotane''': Selectively destroys the zona fasciculata and zona reticularis while sparing the zona glomerulosa. Need to use an induction dose followed by a maintenance dose.
*'''Mitotane''': Selectively destroys the zona fasciculata and zona reticularis while sparing the zona glomerulosa. Need to use an induction dose followed by a maintenance dose.
*'''Trilostane''': Synthetic steroid analogue. Competitively inhibits enzymes of sterois synthesis.
*'''Trilostane''': Synthetic steroid analogue. Competitively inhibits enzymes of steroid synthesis.
*'''L-Deprenyl''': Monoamine oxidase inhibitor. Increases dopamine input to hypothalamus and pituitary and so inhibits ACTH secretion.
*'''L-Deprenyl''': Monoamine oxidase inhibitor. Increases dopamine input to hypothalamus and pituitary and so inhibits ACTH secretion.
Pituitary tumours may be treated with ''radiotherapy'' or ''surgery''.
Pituitary tumours may be treated with ''radiotherapy'' or ''surgery''.