Changes

** Is particularly seen in viral conditions of epithelial tissue.

** Is particularly seen in viral conditions of epithelial tissue.

* [[Oral Cavity - Cavity & Gingiva#Foot and Mouth disease|Foot and Mouth Disease]] is the best example.

* [[Oral Cavity - Cavity & Gingiva#Foot and Mouth disease|Foot and Mouth Disease]] is the best example.

** The virus attacks the stratum spinosum of the epithelium of the tongue and feet.  

** Foot and Mouth virus attacks the stratum spinosum of the epithelium of the tongue and feet.  

*** Affected cells are balloon up with water containing the replicating virus.

** Affected cells balloon up with water containing the replicating virus, swelling until they burst.  

*** Cells swell until they burst.

*** The fluid contained in the cells then forms microvesicles (blisters) in the stratum spinosum.

**** The fluid they contained in the cells then forms microvesicles (blisters) in this layer of the epithelium.

**** Blisters may later burst, shedding vast quantities of the virus.

***** May later burst, shedding vast quantities of the virus. W

** On bursting, the edges of the erosions look ragged.

***** When it bursts, the edges of the erosion look ragged, but within weeks the germinal epithelium at the base of the erosion regenerates the epithelium, leaving no trace of a scar.

*** Within weeks, the germinal epithelium at the base of the erosion regenerates the epithelium, leaving no trace of a scar.

====Vacuolar Degeneration====

====Vacuolar Degeneration====