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→Appearance of Fatty Change
* Fatty change can be readily recognised at post-mortem.
* Fatty change can be readily recognised at post-mortem.
====Appearance of Fatty Change====
==== Gross Appearance of Fatty Change====
* '''Liver'''
* '''Liver'''
** This is the main organ involved in fatty change.
** This is the main organ involved in fatty change.
** May be greatly increased in size.
** Is tan to yellowish in colour.
*** Is normally reddish brown.
** Very prone to rupture with slight pressure (friable).
** Parenchyma bulges outwards on being freed from the constraint of the capsule when cut.
** Parenchyma is dull, yellowish and greasy.
* '''Kidney'''
* '''Kidney'''
** The cortex appears paler.
** The cortex appears paler.
*** Diffuse paleness is not the prominent feature, unlike in the liver.
*** Diffuse paleness is not the prominent feature, unlike in the liver.
* '''Heart'''
* '''Heart'''
** Anoxia, as a result of anaemia, causes fatty change.
** The heart is flabby.
muscles (those furthest away from the blood supply).
** Fatty change may occur as streaks in the papillary muscles.
*** I.e. those muscles furthest away from the blood supply.
** Contractile ability is reduced, and blood is therefore not umped efficiently.
appears as globules or
vacuoles of varying size
====Histological Appearance of Fatty Change====
in the cytoplasm of the
*** The fat appears either as globules or in varying sizes of vacuoles in the cytoplasm.
In the heart, it
appears as tiny groups of
appears as tiny groups of
vacuoles dispersed along
vacuoles dispersed along