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, 23:39, 16 February 2010
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[[Image:Pemphigus donkey.jpg|right|thumb|200px|<small><center>''Pemphigus foliaceous''-like syndrome in a donkey (Image courtesy of [http://drupal.thedonkeysanctuary.org.uk The Donkey Sanctuary])</center></small>]]
[[Image:Pemphigus donkey 2.jpg|right|thumb|200px|<small><center>''Pemphigus foliaceous''-like syndrome in a donkey (Image courtesy of [http://drupal.thedonkeysanctuary.org.uk The Donkey Sanctuary])</center></small>]]
A condition that is clinically and pathologically indistinguishable from '''''pemphigus foliaceus''''' that affects the
'''mucocutaneous and hoof-skin junctions''' is encountered from time to time.
==Clinical signs==
The disease can become '''generalised''' and '''hair loss with circular exudative
patches''' may be encountered. It is usually non-pruritic.
An interesting form of the pemphigus group of conditions involves the
'''coronary bands'''. Acute, sometimes painful, chronic, fluctuating dermatitis
with hypertrophy and prominent scaling and crusting is a feature of this
condition. Often the diagnosis is mistaken for [[Laminitis - Donkey|laminitis]].
==Diagnosis==
It can be diagnosed from a '''biopsy''' of a suitable early lesion.
==Treatment==
Treatment is largely unrewarding, but high dose [[Steroids|steroids]] can be
attempted. Probably the best of these is prednisolone at higher doses at first, tapering the dose progressively down to
a minimum effective alternate daily dose. The risks of [[Laminitis - Donkey|laminitis]] following
steroid usage in donkeys have not been defined to D. Knottenbelt's knowledge
and certainly there does not appear to be a higher risk than in horses (in
which D. Knottenbelt believes the risk is heavily overstated).
==References==
* Knottenbelt, D. (2008) Skin disorders In Svendsen, E.D., Duncan, J. and Hadrill, D. (2008) ''The Professional Handbook of the Donkey'', 4th edition, Whittet Books, Chapter 8
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