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36 bytes added ,  08:52, 20 August 2007
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* Here, the mucin forms part of the ground substance between the fibroblasts that produce it.
 
* Here, the mucin forms part of the ground substance between the fibroblasts that produce it.
* A disturbance in the metabolism of the fibroblasts under some circumstances,means the ground substance takes on a
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* A disturbance in the metabolism of the fibroblasts under some circumstances,means the ground substance takes on a bluish hue in H&E sections.
bluish hue in H&E sections.
   
* Mucoid degenration in the heart valves of middle-aged and older dogs is a common example.
 
* Mucoid degenration in the heart valves of middle-aged and older dogs is a common example.
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It occurs primarily in the
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====Mucoid Degeneration in the Heart Valves of the Dog====
mitral valve and is responsible for a
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condition specific for this species
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* Tends to affects middle-aged and older dogs.
called endocardiosis.
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* Primarily occurs in the mitral valve.
It is important and results in slowly
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* Causes '''endocardiosis'''.
developing heart failure due to the
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** A condition specific to the dog.
inability of a heart with swollen
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* Results in slowly developing heart failure
misshapen valves to effectively pump
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**The valves are swollen and misshapen, so the heart cannot pump blood effectively to the circulation from the left ventricle. *** A substantial proportion of the blood passes back into the left atrium, compromising the filling from the pulmonary vein. **** Leads to back pressure on the pulmonary capillaries with oedema formation in the lungs.  
blood from the left ventricle out into
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***** Heard as moist sounds on auscultation of the lungs.
the systemic circulation. A substantial
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***** Reduces the oxygenation of blood leading to exercise intolerance.
portion of the blood passes back into
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**** Failure of the left side eventually compromises the function of the right side.
the left
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***** There is pooling of blood in the venous system i.e. in the liver.
atrium and compromises the filling of the atrium from the pulmonary vein. This leads to
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back pressure on the pulmonary capillaries with oedema formation in the lungs. This
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20
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reduces the oxygenation of blood leading to exercise intolerance and may be heard as moist
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sounds on auscultation of the lungs. Eventually, this failure of the left side compromises the
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function of the right side and there is also pooling of blood in the venous system i.e. in the liver.
      
===Hyaline Degeneration===
 
===Hyaline Degeneration===
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