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radiation but the availably of teletherapy and interstitial brachytherapy is
radiation but the availably of teletherapy and interstitial brachytherapy is
very limited. The expense and practicality are severely limiting factors.
very limited. The expense and practicality are severely limiting factors.
==Cell Transformation==
[[Image:Wound sarcoid.jpg|left|thumb|250px|<small><center>Sarcoid (Image courtesy of [http://drupal.thedonkeysanctuary.org.uk The Donkey Sanctuary])</center></small>]]
[[Image:Sarcoid removed wound.jpg|right|thumb|250px|<small><center>Wound following removal of sarcoid (Image courtesy of [http://drupal.thedonkeysanctuary.org.uk The Donkey Sanctuary])</center></small>]]
[[Image:Healing of sarcoid wound.jpg|right|thumb|250px|<small><center>Healing of wound (Image courtesy of [http://drupal.thedonkeysanctuary.org.uk The Donkey Sanctuary])</center></small>]]
[[Sarcoid - Donkey|Sarcoid]] transformation at wound sites is a very common (and increasingly important) reason
for wound healing failure. Sarcoid fibroblasts are a strong inhibitor of wound healing and the extent
of the sarcoid within the wound/granulation tissue needs not to be high for inhibition to occur. The
extent of the transformation is sometimes very limited but the effects remain profound. Healing
is inhibited until all tumour cells are removed.
Confirmation of the problem is not always easy. Multiple biopsies from different parts of the tissue should be taken to ensure the maximum chance of finding it.
Special precautions such as early dressing application and particularly
control of fly contact should be taken to protect wounds on donkeys that
already have sarcoids at other sites. Wounds that involve sarcoid tissue
are extremely dangerous because they are very difficult and sometimes
impossible to treat.
==References==
==References==