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{{toplink
 
{{toplink
|backcolour = FAFAD2
   
|linkpage =Endocrine System - Anatomy & Physiology
 
|linkpage =Endocrine System - Anatomy & Physiology
 
|linktext =Endocrine System
 
|linktext =Endocrine System
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|subtext2=FLASH CARDS
 
|subtext2=FLASH CARDS
 
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<FlashCard questions="10">
<center>''In order to reveal an answer, highlight the bulleted area using your mouse.''</center>
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|q1=Describe embryological origin of the Thyroid Gland.
 
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|a1=The thyroid gland is a downgrowth from the pharyngeal endoderm of the developing tongue.  
 
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|l1=Thyroid Gland - Anatomy & Physiology
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|q2=Describe the location of the thyroid gland, it's closely associated structures and anatomical landmarks.
!width="250"|'''Question'''
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|a2=
!width="500"|'''Answer'''
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!width="50"|'''Article'''
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|-
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|<big>Describe embryological origin of the Thyroid Gland.
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*The thyroid gland is a downgrowth from the pharyngeal endoderm of the developing tongue.  
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||[[Thyroid Gland - Anatomy & Physiology|Answer article]]
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|-
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|<big>Describe the location of the thyroid gland, it's closely associated structures and anatomical landmarks.
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*The thyroid gland is adjacent to the cranial part of the trachea, closely associated with the Parathyroid Glands which may be within or close to the thyroid gland itself.
 
*The thyroid gland is adjacent to the cranial part of the trachea, closely associated with the Parathyroid Glands which may be within or close to the thyroid gland itself.
 
*Close to the thyroid gland are the ''Sternohyoid'' and ''Sternothyroid'' muscles, the ''recurrent laryngeal'' nerve and the ''carotid sheath''.
 
*Close to the thyroid gland are the ''Sternohyoid'' and ''Sternothyroid'' muscles, the ''recurrent laryngeal'' nerve and the ''carotid sheath''.
||[[Thyroid Gland - Anatomy & Physiology|Answer article]]
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|l2=Thyroid Gland - Anatomy & Physiology
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|q3=Describe the blood supply and venous drainage of the Thyroid Gland.
|<big>Describe the blood supply and venous drainage of the Thyroid Gland.
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|a3=
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*Supply = Cranial Thyroid Artery and Caudal Thyroid Artery
 
*Supply = Cranial Thyroid Artery and Caudal Thyroid Artery
 
*Venous Drainage = Thyroid Vein (leading to Internal Jugular Vein).
 
*Venous Drainage = Thyroid Vein (leading to Internal Jugular Vein).
||[[Thyroid Gland - Anatomy & Physiology|Answer article]]
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|l3=Thyroid Gland - Anatomy & Physiology
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|q4=The Thyroid gland consists of various sized follicles. What is the name of the cells which line the lumen of the follicles, and what is their function?
|<big>The Thyroid gland consists of various sized follicles. What is the name of the cells which line the lumen of the follicles, and what is their function?
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|a4=Follicular Cells - these synthesize thyroglobulin in their golgi apparatus. Thyroglobulin is a glycoprotein consisting of 70 linked ''tyrosine'' molecules and is the source of thyroid hormones.
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|l4=Thyroid Gland - Anatomy & Physiology
* Follicular Cells - these synthesize thyroglobulin in their golgi apparatus. Thyroglobulin is a glycoprotein consisting of 70 linked ''tyrosine'' molecules and is the source of thyroid hormones.
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|q5=Label the following histological section:
||[[Thyroid Gland - Anatomy & Physiology|Answer article]]
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|-
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|<big>Label the following histological section:
   
[[Image:ThyroidGlandFlashCard1.jpg|left|thumb|250px|©RVC 2008]]
 
[[Image:ThyroidGlandFlashCard1.jpg|left|thumb|250px|©RVC 2008]]
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|a5=
 
*A = Connective Tissue Capsule
 
*A = Connective Tissue Capsule
 
*B = Thyroid Follicles
 
*B = Thyroid Follicles
 
*C = Connective Tissue Septum
 
*C = Connective Tissue Septum
 
*D = Blood Vessels in Capsule.
 
*D = Blood Vessels in Capsule.
||[[Thyroid Gland - Anatomy & Physiology#Histology Gallery|Answer Article]]
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|l5=Thyroid Gland - Anatomy & Physiology#Histology Gallery
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|q6=Which Letter represents the location of the C-Cells of the Thyroid Gland, and what is their function in 'Image 1' below?
|<big>Which Letter represents the location of the C-Cells of the Thyroid Gland, and what is their function?
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|a6=
[[Image:ThyroidGlandFlashCard.jpg|left|thumb|250px|©RVC 2008]]
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*A represents the C Cells.
 
*A represents the C Cells.
 
*The C-Cells (aka Parafollicular Cells) produce Calcitonin, a hormone which acts to lower the plasma calcium level.
 
*The C-Cells (aka Parafollicular Cells) produce Calcitonin, a hormone which acts to lower the plasma calcium level.
||[[Thyroid Gland - Anatomy & Physiology#Ultrastructure and Histology|Answer Article]]
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|l6=Thyroid Gland - Anatomy & Physiology#Ultrastructure and Histology
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|q7=Define and describe the process of ''Iodide Trapping''.
|<big>Define and describe the process of ''Iodide Trapping''.
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|a7=
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*Iodide trapping is the process by which Iodide molecules (I-) are concentrated in the colloid at a level up to 250x greater than the plasma level.  
 
*Iodide trapping is the process by which Iodide molecules (I-) are concentrated in the colloid at a level up to 250x greater than the plasma level.  
 
*The Na+/I- symport in the basal membrane of the follicular cells moves the iodine from the plasma, into the cell. From here is is transported into the colloid.  
 
*The Na+/I- symport in the basal membrane of the follicular cells moves the iodine from the plasma, into the cell. From here is is transported into the colloid.  
 
*The follicular cells and the pumps function in response to Thyroid Stimulating Hormone from the Pituitary Gland.
 
*The follicular cells and the pumps function in response to Thyroid Stimulating Hormone from the Pituitary Gland.
||[[Thyroid Gland - Anatomy & Physiology#Iodine Uptake|Answer Article]]
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|l7=Thyroid Gland - Anatomy & Physiology#Iodine Uptake
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|q8=Name the three hormones produced in the thyroid gland and describe how they are transported around the body?
|<big>Name the three hormones produced in the thyroid gland and describe how they are transported around the body?
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|a8=
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*Hormones: Triiodothyronine (T3), Thyroxine (T4) and Reverse T3.
 
*Hormones: Triiodothyronine (T3), Thyroxine (T4) and Reverse T3.
 
*Thyroid hormones are lipid soluble, thus require a binding protein in order to travel in the bloodstream. Thyroid Binding Globulin caries 70-80% of the circulating hormone, with Thyroxine Binding Pre-Albumin, and Albumin carrying the remainder.
 
*Thyroid hormones are lipid soluble, thus require a binding protein in order to travel in the bloodstream. Thyroid Binding Globulin caries 70-80% of the circulating hormone, with Thyroxine Binding Pre-Albumin, and Albumin carrying the remainder.
||[[Thyroid Gland - Anatomy & Physiology#Transport|Answer article]]
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|l8=Thyroid Gland - Anatomy & Physiology#Transport
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|q9=What are Hormone A and Hormone B in this schematic diagram ('Image 2' below) of the Hypothalamic - Pituitary - Thyroid Axis:
|<big>What are Hormone A and Hormone B in this schematic diagram of the Hypothalamic - Pituitary - Thyroid Axis:
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|a9=
[[Image:ThyroidGlandFlashCard3.jpg|left|thumb|250px]]
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*Hormone A = TRH - Thyrotropin Releasing Hormone
 
*Hormone A = TRH - Thyrotropin Releasing Hormone
 
*Hormone B = TSH - Thyroid Stimulating Hormone (Thyrotropin)
 
*Hormone B = TSH - Thyroid Stimulating Hormone (Thyrotropin)
||[[Thyroid Gland - Anatomy & Physiology#Regulation|Answer article]]
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|l9=Thyroid Gland - Anatomy & Physiology#Regulation
|-
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|q10=Decribe the effects that T3 and T4 have on the following systems/physiological mechanisms:
|<big>Decribe the effects that T3 and T4 have on the following systems/physiological mechanisms:
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|a10=
 
*Musculoskeletal System
 
*Musculoskeletal System
 
*Carbohydrate metabolism
 
*Carbohydrate metabolism
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*Nervous System
 
*Nervous System
 
*Alimentary System
 
*Alimentary System
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*Musculoskeletal system - Thyroid hormone promotes bone growth  
*'''Musculoskeletal system''' - Thyroid hormone promotes bone growth  
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*Carbohydrate metabolism - Thyroid hormone stimulates glucose uptake, glycolysis, gluconeogenesis  
*'''Carbohydrate metabolism''' - Thyroid hormone stimulates glucose uptake, glycolysis, gluconeogenesis  
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*Fat metabolism - Thyroid hormone mobilises lipids from adipose stores. Accelerates oxidation of lipids to produce energy (occurs within mitochondria). Increases size and number of mitochondria.  
*'''Fat metabolism''' - Thyroid hormone mobilises lipids from adipose stores. Accelerates oxidation of lipids to produce energy (occurs within mitochondria). Increases size and number of mitochondria.  
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*Basal Metabolic Rate (BMR) - Thyroid hormone causes and increase in BMR in all tissues except brain, spleen, gonads. Results in increased heat production, increased oxygen consumption.  
*'''Basal Metabolic Rate''' (BMR) - Thyroid hormone causes and increase in BMR in all tissues except brain, spleen, gonads. Results in increased heat production, increased oxygen consumption.  
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*Cardiovascular actions - Thyroid hormone increases Cardiac output, heart rate and contractility.  
*'''Cardiovascular actions''' - Thyroid hormone increases Cardiac output, heart rate and contractility.  
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*Nervous system - thyroid hormones are required for development of this system. They also enhance the sympathetic nervous system (by increasing epinephrine receptors).  
*'''Nervous system''' - thyroid hormones are required for development of this system. They also enhance the sympathetic nervous system (by increasing epinephrine receptors).  
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*Alimentary System - Thyroid hormone increases appetite and feed intake, increases secretion of pancreatic enzymes and increases motility.  
*'''Alimentary System''' - Thyroid hormone increases appetite and feed intake, increases secretion of pancreatic enzymes and increases motility.  
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|l10=Thyroid Gland - Anatomy & Physiology#Thyroid Hormone Actions
||[[Thyroid Gland - Anatomy & Physiology#Thyroid Hormone Actions|Answer article]]
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</FlashCard>
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{|
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|Image 1
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|[[Image:ThyroidGlandFlashCard.jpg|350px|©RVC 2008]]
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|-
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|Image 2
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|[[Image:ThyroidGlandFlashCard3.jpg|350px]]
 
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