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| |linkpage =Endocrine System - Anatomy & Physiology | | |linkpage =Endocrine System - Anatomy & Physiology |
| |linktext =Endocrine System | | |linktext =Endocrine System |
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| |subtext2=FLASH CARDS | | |subtext2=FLASH CARDS |
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− | <br> | + | <FlashCard questions="10"> |
− | <center>''In order to reveal an answer, highlight the bulleted area using your mouse.''</center>
| + | |q1=Describe embryological origin of the Thyroid Gland. |
− | | + | |a1=The thyroid gland is a downgrowth from the pharyngeal endoderm of the developing tongue. |
− | | + | |l1=Thyroid Gland - Anatomy & Physiology |
− | {| border="3" cellpadding="8"
| + | |q2=Describe the location of the thyroid gland, it's closely associated structures and anatomical landmarks. |
− | !width="250"|'''Question'''
| + | |a2= |
− | !width="500"|'''Answer'''
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− | !width="50"|'''Article'''
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− | |<big>Describe embryological origin of the Thyroid Gland.
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− | ||<font color="white"> <big> | |
− | *The thyroid gland is a downgrowth from the pharyngeal endoderm of the developing tongue.
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− | ||[[Thyroid Gland - Anatomy & Physiology|Answer article]] | |
− | |- | |
− | |<big>Describe the location of the thyroid gland, it's closely associated structures and anatomical landmarks.
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− | ||<font color="white"> <big> | |
| *The thyroid gland is adjacent to the cranial part of the trachea, closely associated with the Parathyroid Glands which may be within or close to the thyroid gland itself. | | *The thyroid gland is adjacent to the cranial part of the trachea, closely associated with the Parathyroid Glands which may be within or close to the thyroid gland itself. |
| *Close to the thyroid gland are the ''Sternohyoid'' and ''Sternothyroid'' muscles, the ''recurrent laryngeal'' nerve and the ''carotid sheath''. | | *Close to the thyroid gland are the ''Sternohyoid'' and ''Sternothyroid'' muscles, the ''recurrent laryngeal'' nerve and the ''carotid sheath''. |
− | ||[[Thyroid Gland - Anatomy & Physiology|Answer article]] | + | |l2=Thyroid Gland - Anatomy & Physiology |
− | |- | + | |q3=Describe the blood supply and venous drainage of the Thyroid Gland. |
− | |<big>Describe the blood supply and venous drainage of the Thyroid Gland.
| + | |a3= |
− | ||<font color="white"> <big> | |
| *Supply = Cranial Thyroid Artery and Caudal Thyroid Artery | | *Supply = Cranial Thyroid Artery and Caudal Thyroid Artery |
| *Venous Drainage = Thyroid Vein (leading to Internal Jugular Vein). | | *Venous Drainage = Thyroid Vein (leading to Internal Jugular Vein). |
− | ||[[Thyroid Gland - Anatomy & Physiology|Answer article]] | + | |l3=Thyroid Gland - Anatomy & Physiology |
− | |- | + | |q4=The Thyroid gland consists of various sized follicles. What is the name of the cells which line the lumen of the follicles, and what is their function? |
− | |<big>The Thyroid gland consists of various sized follicles. What is the name of the cells which line the lumen of the follicles, and what is their function?
| + | |a4=Follicular Cells - these synthesize thyroglobulin in their golgi apparatus. Thyroglobulin is a glycoprotein consisting of 70 linked ''tyrosine'' molecules and is the source of thyroid hormones. |
− | ||<font color="white"> <big> | + | |l4=Thyroid Gland - Anatomy & Physiology |
− | * Follicular Cells - these synthesize thyroglobulin in their golgi apparatus. Thyroglobulin is a glycoprotein consisting of 70 linked ''tyrosine'' molecules and is the source of thyroid hormones.
| + | |q5=Label the following histological section: |
− | ||[[Thyroid Gland - Anatomy & Physiology|Answer article]] | |
− | |- | |
− | |<big>Label the following histological section:
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| [[Image:ThyroidGlandFlashCard1.jpg|left|thumb|250px|©RVC 2008]] | | [[Image:ThyroidGlandFlashCard1.jpg|left|thumb|250px|©RVC 2008]] |
− | ||<font color="white"> <big> | + | |a5= |
| *A = Connective Tissue Capsule | | *A = Connective Tissue Capsule |
| *B = Thyroid Follicles | | *B = Thyroid Follicles |
| *C = Connective Tissue Septum | | *C = Connective Tissue Septum |
| *D = Blood Vessels in Capsule. | | *D = Blood Vessels in Capsule. |
− | ||[[Thyroid Gland - Anatomy & Physiology#Histology Gallery|Answer Article]] | + | |l5=Thyroid Gland - Anatomy & Physiology#Histology Gallery |
− | |- | + | |q6=Which Letter represents the location of the C-Cells of the Thyroid Gland, and what is their function in 'Image 1' below? |
− | |<big>Which Letter represents the location of the C-Cells of the Thyroid Gland, and what is their function?
| + | |a6= |
− | [[Image:ThyroidGlandFlashCard.jpg|left|thumb|250px|©RVC 2008]]
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− | ||<font color="white"> <big>
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| *A represents the C Cells. | | *A represents the C Cells. |
| *The C-Cells (aka Parafollicular Cells) produce Calcitonin, a hormone which acts to lower the plasma calcium level. | | *The C-Cells (aka Parafollicular Cells) produce Calcitonin, a hormone which acts to lower the plasma calcium level. |
− | ||[[Thyroid Gland - Anatomy & Physiology#Ultrastructure and Histology|Answer Article]] | + | |l6=Thyroid Gland - Anatomy & Physiology#Ultrastructure and Histology |
− | |- | + | |q7=Define and describe the process of ''Iodide Trapping''. |
− | |<big>Define and describe the process of ''Iodide Trapping''.
| + | |a7= |
− | ||<font color="white"> <big> | |
| *Iodide trapping is the process by which Iodide molecules (I-) are concentrated in the colloid at a level up to 250x greater than the plasma level. | | *Iodide trapping is the process by which Iodide molecules (I-) are concentrated in the colloid at a level up to 250x greater than the plasma level. |
| *The Na+/I- symport in the basal membrane of the follicular cells moves the iodine from the plasma, into the cell. From here is is transported into the colloid. | | *The Na+/I- symport in the basal membrane of the follicular cells moves the iodine from the plasma, into the cell. From here is is transported into the colloid. |
| *The follicular cells and the pumps function in response to Thyroid Stimulating Hormone from the Pituitary Gland. | | *The follicular cells and the pumps function in response to Thyroid Stimulating Hormone from the Pituitary Gland. |
− | ||[[Thyroid Gland - Anatomy & Physiology#Iodine Uptake|Answer Article]] | + | |l7=Thyroid Gland - Anatomy & Physiology#Iodine Uptake |
− | |- | + | |q8=Name the three hormones produced in the thyroid gland and describe how they are transported around the body? |
− | |<big>Name the three hormones produced in the thyroid gland and describe how they are transported around the body?
| + | |a8= |
− | ||<font color="white"> <big> | |
| *Hormones: Triiodothyronine (T3), Thyroxine (T4) and Reverse T3. | | *Hormones: Triiodothyronine (T3), Thyroxine (T4) and Reverse T3. |
| *Thyroid hormones are lipid soluble, thus require a binding protein in order to travel in the bloodstream. Thyroid Binding Globulin caries 70-80% of the circulating hormone, with Thyroxine Binding Pre-Albumin, and Albumin carrying the remainder. | | *Thyroid hormones are lipid soluble, thus require a binding protein in order to travel in the bloodstream. Thyroid Binding Globulin caries 70-80% of the circulating hormone, with Thyroxine Binding Pre-Albumin, and Albumin carrying the remainder. |
− | ||[[Thyroid Gland - Anatomy & Physiology#Transport|Answer article]] | + | |l8=Thyroid Gland - Anatomy & Physiology#Transport |
− | |- | + | |q9=What are Hormone A and Hormone B in this schematic diagram ('Image 2' below) of the Hypothalamic - Pituitary - Thyroid Axis: |
− | |<big>What are Hormone A and Hormone B in this schematic diagram of the Hypothalamic - Pituitary - Thyroid Axis:
| + | |a9= |
− | [[Image:ThyroidGlandFlashCard3.jpg|left|thumb|250px]]
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− | ||<font color="white"> <big>
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| *Hormone A = TRH - Thyrotropin Releasing Hormone | | *Hormone A = TRH - Thyrotropin Releasing Hormone |
| *Hormone B = TSH - Thyroid Stimulating Hormone (Thyrotropin) | | *Hormone B = TSH - Thyroid Stimulating Hormone (Thyrotropin) |
− | ||[[Thyroid Gland - Anatomy & Physiology#Regulation|Answer article]] | + | |l9=Thyroid Gland - Anatomy & Physiology#Regulation |
− | |- | + | |q10=Decribe the effects that T3 and T4 have on the following systems/physiological mechanisms: |
− | |<big>Decribe the effects that T3 and T4 have on the following systems/physiological mechanisms:
| + | |a10= |
| *Musculoskeletal System | | *Musculoskeletal System |
| *Carbohydrate metabolism | | *Carbohydrate metabolism |
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| *Nervous System | | *Nervous System |
| *Alimentary System | | *Alimentary System |
− | ||<font color="white"> <big>
| + | *Musculoskeletal system - Thyroid hormone promotes bone growth |
− | *'''Musculoskeletal system''' - Thyroid hormone promotes bone growth | + | *Carbohydrate metabolism - Thyroid hormone stimulates glucose uptake, glycolysis, gluconeogenesis |
− | *'''Carbohydrate metabolism''' - Thyroid hormone stimulates glucose uptake, glycolysis, gluconeogenesis | + | *Fat metabolism - Thyroid hormone mobilises lipids from adipose stores. Accelerates oxidation of lipids to produce energy (occurs within mitochondria). Increases size and number of mitochondria. |
− | *'''Fat metabolism''' - Thyroid hormone mobilises lipids from adipose stores. Accelerates oxidation of lipids to produce energy (occurs within mitochondria). Increases size and number of mitochondria. | + | *Basal Metabolic Rate (BMR) - Thyroid hormone causes and increase in BMR in all tissues except brain, spleen, gonads. Results in increased heat production, increased oxygen consumption. |
− | *'''Basal Metabolic Rate''' (BMR) - Thyroid hormone causes and increase in BMR in all tissues except brain, spleen, gonads. Results in increased heat production, increased oxygen consumption. | + | *Cardiovascular actions - Thyroid hormone increases Cardiac output, heart rate and contractility. |
− | *'''Cardiovascular actions''' - Thyroid hormone increases Cardiac output, heart rate and contractility. | + | *Nervous system - thyroid hormones are required for development of this system. They also enhance the sympathetic nervous system (by increasing epinephrine receptors). |
− | *'''Nervous system''' - thyroid hormones are required for development of this system. They also enhance the sympathetic nervous system (by increasing epinephrine receptors). | + | *Alimentary System - Thyroid hormone increases appetite and feed intake, increases secretion of pancreatic enzymes and increases motility. |
− | *'''Alimentary System''' - Thyroid hormone increases appetite and feed intake, increases secretion of pancreatic enzymes and increases motility. | + | |l10=Thyroid Gland - Anatomy & Physiology#Thyroid Hormone Actions |
− | ||[[Thyroid Gland - Anatomy & Physiology#Thyroid Hormone Actions|Answer article]] | + | </FlashCard> |
| + | {| |
| + | |Image 1 |
| + | |[[Image:ThyroidGlandFlashCard.jpg|350px|©RVC 2008]] |
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| + | |Image 2 |
| + | |[[Image:ThyroidGlandFlashCard3.jpg|350px]] |
| |} | | |} |