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Drug Administration - Donkey (view source)
Revision as of 22:07, 20 February 2010
, 22:07, 20 February 2010no edit summary
==Drug administration==
==Drug administration==
The parenteral (e.g. intravenous, intramuscular, subcutaneous, intra-articular)
The parenteral (''e.g.'' intravenous, intramuscular, subcutaneous, intra-articular)
or oral routes are used most commonly to administer drugs to donkeys.
or oral routes are used most commonly to administer drugs to donkeys.
The choice of administration route depends on a number of factors,
The choice of administration route depends on a number of factors,
drugs by this route, e.g. atropine has systemic effects following ophthalmic
drugs by this route, e.g. atropine has systemic effects following ophthalmic
administration.
administration.
<center>'''Factors to consider when selecting an administration route.'''
{| cellpadding="10" cellspacing="0" border="1"
|'''intravenous (i.v.)'''
| '''intramuscular (i.m.)/ subcutaneous (s.c.)'''
| '''''per os'', oral (p.o.)'''
|-
|Rapidly produces high drug concentrations in the circulation
|Gives better and more consistent absorption than s.c.
|Rate and extent of absorption can be highly variable
|-
|Can titrate to effect(''e.g.'' anaesthetics)
|No more than 30ml per injection site
|Bioavailability of drugs can be substantially decreased
|-
|Increased chance of adverse reactions
|Donkeys less sensitive to local side effects (irritation, infection) than horses
|Absorption can be delayed or biphasic due to adsorption onto feed
|-
|Bioavailability 100%
|.
|Usually safe
|-
}
</center>
==References==
==References==