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Tetrahydropyrimidines (''e.g.''''' pyrantel embonate''') are active against adult and luminal stages of [[Strongyles - Donkey|strongyles]] and [[Ascarids - Donkey|ascarids]] but have only LIMITED efficacy against migrating larval parasites and NO activity against [[Bots - Donkey|bots]]. Double dose rates can be used to treat [[Tapeworm - Donkey|tapeworms]].
 
Tetrahydropyrimidines (''e.g.''''' pyrantel embonate''') are active against adult and luminal stages of [[Strongyles - Donkey|strongyles]] and [[Ascarids - Donkey|ascarids]] but have only LIMITED efficacy against migrating larval parasites and NO activity against [[Bots - Donkey|bots]]. Double dose rates can be used to treat [[Tapeworm - Donkey|tapeworms]].
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==[[Anthelmintic Resistance|Resistance to anthelmintics]]==
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Frequent use of [[Anthelmintic Drugs|anthelmintics]] and sub-optimal dosing has been implicated in the selection for resistant nematodes. Egg counts should be used as a guide to worming. Weigh the donkey or estimate its weight using the [[Heart Girth Nomogram - Donkey|nomogram]] to allow more accurate worm dosing.
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Previous trials at [http://drupal.thedonkeysanctuary.org.uk/ the Donkey Sanctuary] suggest that resistance to the benzimidazole and pyrantel derivatives is developing. Recent trials have indicated that resistance to [[Macrocyclic Lactones|moxidectin]] may be developing. Future development in biological control using nematode-trapping fungi is being studied.
    
==References==
 
==References==
Author, Donkey, Bureaucrats, Administrators
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