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| ''[[Actinobacillus pleuropneumoniae]]'' | | ''[[Actinobacillus pleuropneumoniae]]'' |
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| + | ''[[Actinobacillus equuli]]'' |
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− | ===''Actinobacillus equuli''===
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− | *Commensal of the equine intestinal and reproductive tract
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− | *Pathogenesis and clinical signs:
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− | **Foals infected ''in utero'' or or after birth via the umbilicus
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− | **Infection at birth causes severe enteritis and septicaemia within 24 hours, known as sleepy foal disease
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− | **Foals become pyrexic and recumbent
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− | **Death usually occurs within 1-2 days
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− | **In foals that survive neonatal infection the condition progresses to cause joint infections and purulent nephritis, enteritis or pneumonia
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− | **''A. equuli'' in [[Joints Inflammatory - Pathology#In Horses|arthritis of horses]]
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− | **Abortion, septicaemia and [[Peritoneal Cavity Inflammatory - Pathology#In horses|peritonitis in horses]]
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− | *Diagnosis:
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− | **Specimens cultured on blood agar and MacConkey agar and incubated aerobically for 1-3 days
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− | **Sticky colonies with variable haemolysis on blood agar
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− | **Lactose-fermenting colonies on MacConkey agar
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− | *Treatment and control:
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− | **Antimicrobials ineffective unless early in course of disease
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− | **Blood trasfusion and administration of colostrum
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− | **Good hygiene
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− | **Consider prophylactic antibiotics for new-born foals
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− | **Bacteria susceptible to streptomycin, tetracyclines and ampicillin
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− | *In other animals:
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− | **Septicaemia in piglets
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− | **Arthritis and enteritis in pigs
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− | **Enteritis in calves
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− | **RTX group cytotoxin present
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