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Created page with '*Characteristics: **Formerly known as ''Actinomyces pyogenes'' and ''Corynebacterium pyogenes'' **Small facultatively anaerobic rod **Grows slowly on blood agar to produce small,…'
*Characteristics:
**Formerly known as ''Actinomyces pyogenes'' and ''Corynebacterium pyogenes''
**Small facultatively anaerobic rod
**Grows slowly on blood agar to produce small, white colonies surrounded by a zone of beta-haemolysis after 48 hours
**Produces hazy haemolysis after 24 hours; pin-point colonies after 48 hours
**Coryneform morphology, like Chinese characters; may be curved with slightly swollen ends
**Found in nasopharyngeal mucosa and genital tract of cattle, sheep, pigs
*Pathogenicity''
**Opportunistic infections following injury or viral/mycoplasma infection in ruminants and pigs
**Extracellular toxins including haemolysin, proteases, DNase and neurominidase
**Haemolytic toxin, pyolysin, member of the thiol-activated cytolysins (pore-forming toxins); possibly cytotoxic to phagocytic cells; dermonecrotising activity
*Clinical infections:
**Suppurative infections
**Abscesses especially in liver
**Lymphadenitis, [[Bones Inflammatory - Pathology#Osteomyelitis|osteomyelitis]], peritonitis and neural abscessation
**Pyometra
**Endometritis
**Summer mastitis
**Ovine foot disease
**[[Joints Inflammatory - Pathology#In Sheep|Arthritis]] of sheep post-dipping; [[Joints Inflammatory - Pathology#In Pigs|arthritis in pigs]] and [[Joints Inflammatory - Pathology#In Cattle|arthritis in cattle]]
**Umbilical infections
**[[Respiratory Bacterial Infections - Pathology#Acute exudative pneumonia|Acute exudative pneumonia]] and contributes to [[Respiratory Bacterial Infections - Pathology#Enzootic pneumonia of calves|Enzootic pneumonia of calves]]
**May cause [[Muscles Inflammatory - Pathology#Abscesses|myositis]]
**Unclassified ''Actinomyces'' species isolated from closed cases of [[Bursae and Tendons Inflammatory - Pathology#Poll Evil and Fistulous Withers|Poll Evil and Fistulous Withers]]
*Treatment:
**Penicillin or broad spectrum antibiotics[[Category:Actinomyces]][[Category:Pig]][[Category:Cattle]]
**Formerly known as ''Actinomyces pyogenes'' and ''Corynebacterium pyogenes''
**Small facultatively anaerobic rod
**Grows slowly on blood agar to produce small, white colonies surrounded by a zone of beta-haemolysis after 48 hours
**Produces hazy haemolysis after 24 hours; pin-point colonies after 48 hours
**Coryneform morphology, like Chinese characters; may be curved with slightly swollen ends
**Found in nasopharyngeal mucosa and genital tract of cattle, sheep, pigs
*Pathogenicity''
**Opportunistic infections following injury or viral/mycoplasma infection in ruminants and pigs
**Extracellular toxins including haemolysin, proteases, DNase and neurominidase
**Haemolytic toxin, pyolysin, member of the thiol-activated cytolysins (pore-forming toxins); possibly cytotoxic to phagocytic cells; dermonecrotising activity
*Clinical infections:
**Suppurative infections
**Abscesses especially in liver
**Lymphadenitis, [[Bones Inflammatory - Pathology#Osteomyelitis|osteomyelitis]], peritonitis and neural abscessation
**Pyometra
**Endometritis
**Summer mastitis
**Ovine foot disease
**[[Joints Inflammatory - Pathology#In Sheep|Arthritis]] of sheep post-dipping; [[Joints Inflammatory - Pathology#In Pigs|arthritis in pigs]] and [[Joints Inflammatory - Pathology#In Cattle|arthritis in cattle]]
**Umbilical infections
**[[Respiratory Bacterial Infections - Pathology#Acute exudative pneumonia|Acute exudative pneumonia]] and contributes to [[Respiratory Bacterial Infections - Pathology#Enzootic pneumonia of calves|Enzootic pneumonia of calves]]
**May cause [[Muscles Inflammatory - Pathology#Abscesses|myositis]]
**Unclassified ''Actinomyces'' species isolated from closed cases of [[Bursae and Tendons Inflammatory - Pathology#Poll Evil and Fistulous Withers|Poll Evil and Fistulous Withers]]
*Treatment:
**Penicillin or broad spectrum antibiotics[[Category:Actinomyces]][[Category:Pig]][[Category:Cattle]]