− | '''Neutrophilic cholangiohepatitis''' is characterised by infiltration of large numbers of [[Neutrophils - WikiBlood|neutrophils]] into portal areas of the [[Liver - Anatomy & Physiology|liver]] and into the [[Liver - Anatomy & Physiology #Hepatic Duct Systems|bile ducts]]. It results from ascending bacterial infection from the [[Small Intestine - Anatomy & Physiology|small intestines]]. [[Escherichia coli]], [[Staphylococcus spp.]], ''[[Streptococci|Streptococcus]] spp.'', ''[[Clostridium species|Clostridium spp.]]'', ''[[Bacillus species|Bacillus spp.]]'', ''[[:Category:Actinomyces|Actinomyces spp.]]'', ''[[Bacteroides|Bacteroides spp.]]'' and occasionally ''[[Salmonella|Salmonella spp.]]'' have been isolated. Concurrent biliary tract disease are common in cats, especially [[Pancreatitis - WikiClinical|pancreatitis]] and [[Inflammatory Bowel Disease - WikiClinical|inflammatory bowel disease]]. Other predisposing factors include congenital or acquired abnormalities of the biliary system such as that of anatomic abnormalities of the [[Gall Bladder - Anatomy & Physiology|gall bladder]] or common bile duct, bile duct obstruction caused by inspissated bile, cholelithiasis and cholecystitis. | + | '''Neutrophilic cholangiohepatitis''' is characterised by infiltration of large numbers of [[Neutrophils - WikiBlood|neutrophils]] into portal areas of the [[Liver - Anatomy & Physiology|liver]] and into the [[Liver - Anatomy & Physiology #Hepatic Duct Systems|bile ducts]]. It results from ascending bacterial infection from the [[Small Intestine - Anatomy & Physiology|small intestines]]. [[Escherichia coli]], [[Staphylococcus spp.]], ''[[Streptococci|Streptococcus]] spp.'', ''[[:Category:Clostridium species|Clostridium spp.]]'', ''[[Bacillus species|Bacillus spp.]]'', ''[[:Category:Actinomyces|Actinomyces spp.]]'', ''[[Bacteroides|Bacteroides spp.]]'' and occasionally ''[[Salmonella|Salmonella spp.]]'' have been isolated. Concurrent biliary tract disease are common in cats, especially [[Pancreatitis - WikiClinical|pancreatitis]] and [[Inflammatory Bowel Disease - WikiClinical|inflammatory bowel disease]]. Other predisposing factors include congenital or acquired abnormalities of the biliary system such as that of anatomic abnormalities of the [[Gall Bladder - Anatomy & Physiology|gall bladder]] or common bile duct, bile duct obstruction caused by inspissated bile, cholelithiasis and cholecystitis. |