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Created page with '===Canine monocytic ehrlichiosis=== *Generalised disease of dogs in tropical and subtropical regions *Caused by ''Ehrlichia canis'' *The brown tick, ''Rhipicephalus sanguineus''…'
===Canine monocytic ehrlichiosis===

*Generalised disease of dogs in tropical and subtropical regions
*Caused by ''Ehrlichia canis''
*The brown tick, ''Rhipicephalus sanguineus'', is the main vector
*Dogs may carry the organism for 2 years after resolution of clinical signs

*Clinical signs
**Incubation period of 3 weeks
**Acute, subclinical or chronic phases
**Acute phase: fever, thrombocytopenia, leukopenia and anaemia
**Subclinical phase: low blood cell numbers but minimal clinical signs; can progress to a severe disease, tropical canine pancytopenia
**Chronic phase: bone marrow depression, haemorrhages, neurological disease, peripheral oedema, emaciation and hypotensive shock

*Diagnosis
**''E. canis'' morulae present in mononuclear cells in Giemsa-stained blood smears
**Rising antibody titre detected by indirect immunofluorescence
**Culture in canine macrophages

*Treatment and control
**Doxycycline for 10 days
**Fluid therapy or blood transfusion
**Prophylactic tetracyclines

[[Category:Rickettsiales]][[Category:Dog]]
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