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[[Staphylococcus aureus]]
 
[[Staphylococcus aureus]]
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===Exudative epidermitis ([[Bacterial skin infections - Pathology#Greasy pig disease|Greasy pig disease]])===
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*Worldwide disease of pigs under 3 months of age caused by ''S. hyicus''
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*Highly contagious and persists in the environment for long periods
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*''S. hyicus'' produces exfoliative toxin that causes separation of cells in stratum spinosum resulting in rapid intraepidermal spread of organisms
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*Similar to “scalded skin syndrome” in human neonates, due to skin infection by exfoliative toxin-producing ''Staphylococcus aureus''
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*Excessive sebacious secretion and exudation on surface of skin
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*Pigs are anorexic, febrile, depressed and have a greasy, non-pruritic dermatitis
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*SKin thickened, wrinkled and scaley
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*Acute death in piglets under 3 weeks due to dehydration and septicaemia
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*20-100% morbidity; up to 90% mortality
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*Organism enters skin via abrasions e.g. bite wounds
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*Carried in vaginal mucosa and skin of sows
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*Predisposed by lack of milk, weaning and other infections
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*Piglets from non-immune sows are predisposed
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*Passive transfer of antibodies from immune sows and development of immunity with age protect against disease
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*Isolation from skin lesions
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*Early systemic antibiotics amd topical antiseptics/antibiotics useful
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*Disinfection after outbreak
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*Wash sows before farrowing
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*Differential diagnosis:
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**Mange (''Sarcoptes scabiei var. suis'')
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**Swine parakeratosis (zinc and essential fatty acid deficiency)
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**Porcine juvenile pustular psoriasiform dermatitis (collarettes or rings typically on the ventrum of young pigs)
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**Dermatosis vegetans (associated with a giant cell pneumonia)
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**Dermatophytosis (most commonly ''Microsporum nanum'')
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[[Staphylococcus hyicus]]
    
===Infections in dogs and cats===
 
===Infections in dogs and cats===
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