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Category:Paramyxoviridae (view source)

Revision as of 11:20, 22 May 2010

543 bytes removed , 11:20, 22 May 2010

→‎Rodentia

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==Rodentia==

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===Murine Parainfluenza - 1 (Sendai ~~virus~~)===

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===Murine Parainfluenza - 1 ([[Sendai Virus]])===

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*Endemic in many '''mouse''' colonies

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*Most mice show no symptoms due to maternal antibodies

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*But minor respiratory lesions may invalidate carcinogenic or toxicological studies

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*Immunological studies also confused due to virus activating [[Lymphocytes - WikiBlood#Natural Killer (NK) Cells|NK cells]] via high circulating [[Innate Immune System - WikiBlood#Interferons|IF]] 3-4 days post-infection

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*Control achieved by:

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**Purchasing '''specific pathogen free (SPF)''' mice

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**Kill whole colony in an outbreak -> disinfection -> formalin fumigation

=Other resources=

Bara

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